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采用关键信息人法评估中国东南部江西省修水县儿童盲症的患病率及病因。

Using key informant method to assess the prevalence and causes of childhood blindness in Xiu'shui County, Jiangxi Province, Southeast China.

作者信息

Xiao Baixiang, Fan Jiangbo, Deng Yan, Ding Yonglei, Muhit Mohammad, Kuper Hannah

机构信息

The Fred Hollows Foundation, China, Nanchang City, China.

出版信息

Ophthalmic Epidemiol. 2011 Feb;18(1):30-5. doi: 10.3109/09286586.2010.528138. Epub 2010 Nov 30.

Abstract

BACKGROUND

Although childhood blindness is relatively rare, it is the leading cause of blind person years besides cataract. The aim of this study is to estimate the prevalence and causes of childhood blindness and severe visual impairment (BL/SVI) in southeast China.

METHODS

The study took place across four administrative units in Xiu'shui County. Sixty key informants were trained by an ophthalmologist to identify possible cases of childhood BL/SVI (children < 16 years with presenting visual acuity < 6/60 in the better eye) in their own communities. The possible cases were referred to a hospital for further examination by a pediatric ophthalmologist, to ascertain case status and determine the cause of BL/SVI.

RESULTS

In total we found 8 cases of childhood BL/SVI from a total population of approximately 27,000 children. The prevalence of childhood BL/SVI was therefore 0.3/1000 (95% Confidence Interval [CI]: 0.1-0.5/1000). The prevalence of blindness (< 3/60) was 0.2/1000 (95% CI: 0.04/1000-0.4/1000) and the prevalence of SVI (< 6/60-3/60) was 0.07/1000 (95% CI: 0-0.17/1000). The main cause of BL/SVI was posterior segment disease (87.5%). Half of the cases were potentially treatable.

CONCLUSIONS

The study has documented a low prevalence of childhood BL/SVI in southeast China. Despite the low prevalence, half of the cases were potentially treatable if earlier medical action was taken, suggesting the prevalence could be reduced further still. The Key Informant Method is simple to implement and an efficient method for case finding in China.

摘要

背景

尽管儿童失明相对罕见,但它是除白内障外导致盲人年数的主要原因。本研究的目的是估计中国东南部儿童失明和严重视力损害(BL/SVI)的患病率及病因。

方法

该研究在修水县的四个行政单位开展。60名关键信息提供者接受了眼科医生的培训,以识别其所在社区可能存在的儿童BL/SVI病例(16岁以下儿童,较好眼的视力<6/60)。这些可能的病例被转诊至医院,由小儿眼科医生进行进一步检查,以确定病例状态并明确BL/SVI的病因。

结果

在约27000名儿童中,我们共发现8例儿童BL/SVI病例。因此,儿童BL/SVI的患病率为0.3/1000(95%置信区间[CI]:0.1 - 0.5/1000)。失明(<3/60)的患病率为0.2/1000(95%CI:0.04/1000 - 0.4/1000),严重视力损害(<6/60 - 3/60)的患病率为0.07/1000(95%CI:0 - 0.17/1000)。BL/SVI的主要病因是后段疾病(87.5%)。一半的病例有可能得到治疗。

结论

该研究记录了中国东南部儿童BL/SVI的低患病率。尽管患病率较低,但如果能更早采取医疗行动,一半的病例有可能得到治疗,这表明患病率仍可进一步降低。关键信息提供者方法在中国易于实施,是一种有效的病例发现方法。

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