Department of Epidemiology, Documentation and Health Promotion, Amsterdam, the Netherlands.
BMC Public Health. 2010 Nov 30;10:740. doi: 10.1186/1471-2458-10-740.
High total cholesterol and low HDL (high-density lipoprotein) cholesterol are important determinants of cardiovascular disease. Little is known about dyslipidemia among Turkish and Moroccan migrants, two of the largest ethnic minority groups in several European countries. This study examines ethnic differences in total and HDL cholesterol levels between Dutch, Turkish and Moroccan ethnic groups.
Data were collected in the setting of a general health survey, in Amsterdam, the Netherlands, in 2004. Total response rate was 45% (Dutch: 46%, Turks: 50%, Moroccans: 39%). From 1,220 adults information on history of hypercholesterolemia, lifestyle and demographic background was obtained via health interviews. In a physical examination measurements of anthropometry and blood pressure were performed and blood was collected. Total and HDL cholesterol were determined in serum.
Total cholesterol levels were lower and hypercholesterolemia was less prevalent among the Moroccan and Turkish than the Dutch ethnic population. HDL cholesterol was also relatively low among these migrant groups. The resulting total/HDL cholesterol ratio was particularly unfavourable among the Turkish ethnic group. Controlling for Body Mass Index and alcohol abstinence substantially attenuated ethnic differences in HDL cholesterol levels and total/HDL cholesterol ratio.
Total cholesterol levels are relatively low in Turkish and Moroccan migrants. However part of this advantage is off-set by their relatively low levels of HDL cholesterol, resulting in an unfavourable total/HDL cholesterol ratio, particularly in the Turkish population. Important factors in explaining ethnic differences are the relatively high Body Mass Index and level of alcohol abstinence in these migrant groups.
高总胆固醇和低高密度脂蛋白（高密度脂蛋白）胆固醇是心血管疾病的重要决定因素。关于土耳其和摩洛哥移民的血脂异常知之甚少，他们是欧洲几个国家中最大的少数民族群体之一。本研究检查了荷兰、土耳其和摩洛哥族裔群体之间总胆固醇和高密度脂蛋白胆固醇水平的种族差异。
数据是在 2004 年荷兰阿姆斯特丹的一项一般健康调查中收集的。总响应率为 45%（荷兰人：46%，土耳其人：50%，摩洛哥人：39%）。从 1220 名成年人中，通过健康访谈获得了有关高胆固醇血症病史、生活方式和人口统计学背景的信息。在体格检查中，测量了人体测量和血压，并采集了血液。在血清中测定总胆固醇和高密度脂蛋白胆固醇。
与荷兰族裔人群相比，摩洛哥和土耳其族裔人群的总胆固醇水平较低，高胆固醇血症的患病率也较低。这些移民群体的高密度脂蛋白胆固醇也相对较低。由此产生的总/高密度脂蛋白胆固醇比值在土耳其族裔人群中尤其不利。控制体重指数和戒酒可大大减弱高密度脂蛋白胆固醇水平和总/高密度脂蛋白胆固醇比值的种族差异。
土耳其和摩洛哥移民的总胆固醇水平相对较低。然而，部分优势因高密度脂蛋白胆固醇水平相对较低而抵消，导致总/高密度脂蛋白胆固醇比值不利，尤其是在土耳其人群中。在解释种族差异方面，重要因素是这些移民群体相对较高的体重指数和戒酒水平。
