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2006 年至 2011 年中国民航飞行员血脂异常的流行病学调查。

Epidemiological survey of dyslipidemia in civil aviators in china from 2006 to 2011.

机构信息

Xi'an Civil Aviation Hospital, Xi'an 710082, China ; Department of Epidemiology and Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, No. 169, Changle West Road, Xi'an 710032, China.

Department of Epidemiology and Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, No. 169, Changle West Road, Xi'an 710032, China.

出版信息

Int J Endocrinol. 2014;2014:215076. doi: 10.1155/2014/215076. Epub 2014 Feb 17.

DOI:10.1155/2014/215076
PMID:24693285
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3947663/
Abstract

Aim. This study aimed to analyze blood lipid levels, temporal trend, and age distribution of dyslipidemia in civil aviators in China. Methods. The 305 Chinese aviators were selected randomly and followed up from 2006 to 2011. Their total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels were evaluated annually. Mean values for each parameter by year were compared using a linear mixed-effects model. The temporal trend of borderline high, high, and low status for each index and of overall borderline high, hyperlipidemia, and dyslipidemia by year was tested using a generalized linear mixed model. Results. The aviators' TC (F = 4.33, P < 0.01), HDL-C (F = 23.25, P < 0.01), and LDL-C (F = 6.13, P < 0.01) values differed across years. The prevalence of dyslipidemia (F = 5.53, P < 0.01), borderline high (F = 6.52, P < 0.01), and hyperlipidemia (F = 3.90, P < 0.01) also differed across years. The prevalence rates for hyperlipidemia and dyslipidemia were the highest in the 41-50-year-old and 31-40-year-old groups. Conclusions. Civil aviators in China were in high dyslipidemia and borderline high level and presented with dyslipidemia younger than other Chinese populations.

摘要

目的。本研究旨在分析中国民航飞行员的血脂水平、时间趋势和血脂异常的年龄分布。

方法。随机选择 305 名中国飞行员,从 2006 年至 2011 年进行随访。每年评估他们的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平。使用线性混合效应模型比较每年各参数的平均值。使用广义线性混合模型检验每年每个指标的边缘高值、高值和低值状态以及整体边缘高值、高脂血症和血脂异常的时间趋势。

结果。飞行员的 TC(F=4.33,P<0.01)、HDL-C(F=23.25,P<0.01)和 LDL-C(F=6.13,P<0.01)值在不同年份之间存在差异。血脂异常(F=5.53,P<0.01)、边缘高值(F=6.52,P<0.01)和高脂血症(F=3.90,P<0.01)的患病率也存在差异。高脂血症和血脂异常的患病率在 41-50 岁和 31-40 岁年龄组中最高。

结论。中国民航飞行员血脂异常和边缘高值水平较高,且较其他中国人群更早出现血脂异常。