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酗酒患者的侵蚀性病变。

Erosive lesions in patients with alcoholism.

机构信息

Department of Pediatric Dentistry, School of Dental Medicine, University of Zagreb, Gunduliceva 5, Zagreb 10000 Croatia.

出版信息

J Am Dent Assoc. 2010 Dec;141(12):1452-8. doi: 10.14219/jada.archive.2010.0107.

DOI:10.14219/jada.archive.2010.0107
PMID:21119129
Abstract

BACKGROUND

The authors conducted a study to determine the occurrence of erosive tooth lesions in patients with alcoholism and to establish the influence of salivary flow rates and pH levels on their appearance.

METHODS

The authors conducted a cross-sectional study in 140 participants (70 with clinically diagnosed alcoholism who were undergoing therapy for their addiction were in the test group and 70 who did not consume alcohol were in the control group). The authors determined the participants' salivary statuses by measuring the flow rates and pH levels of both unstimulated and stimulated saliva.

RESULTS

The authors found more erosive lesions in the test group (P < .01). They detected a higher number of erosive lesions in participants in the test group who had a pH range of 5 to 6 compared with a pH range of 6 to 7 (P = .01). They found a significant correlation between alcoholism and unstimulated salivary flow rate (P < .05).

CONCLUSIONS

The salivary flow rate was similar in control and test groups. The prevalence of erosion in the test group was higher than that in the control group, which may be related to the decrease in salivary pH of both stimulated and unstimulated saliva in this group. The results of the study showed no connection between erosion prevalence and pH levels and stimulated salivary flow rates.

CLINICAL IMPLICATIONS

Patients with alcoholism may be at risk of developing erosive lesions on their teeth owing to the low pH level of their oral environment and decreased saliva levels.

摘要

背景

作者进行了一项研究,以确定酗酒患者中侵蚀性牙损伤的发生情况,并确定唾液流量和 pH 值对其出现的影响。

方法

作者对 140 名参与者进行了横断面研究(70 名被临床诊断为酗酒且正在接受治疗的参与者为实验组,70 名不饮酒的参与者为对照组)。作者通过测量未刺激和刺激唾液的流速和 pH 值来确定参与者的唾液状况。

结果

作者在实验组中发现了更多的侵蚀性病变(P<.01)。与 pH 值为 6 到 7 的范围相比,实验组中 pH 值在 5 到 6 范围内的参与者中检测到更多的侵蚀性病变(P=.01)。作者发现酗酒与未刺激唾液流速之间存在显著相关性(P<.05)。

结论

对照组和实验组的唾液流速相似。实验组的侵蚀患病率高于对照组,这可能与该组刺激和未刺激唾液的 pH 值降低有关。研究结果表明,侵蚀患病率与 pH 值和刺激唾液流速之间没有联系。

临床意义

由于口腔环境的 pH 值较低和唾液水平降低,酗酒患者可能有患侵蚀性牙损伤的风险。

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