Brucoli Matteo, Arcuri Francesco, Stellin Livia, Benech Arnaldo
Department of Maxillo-Facial Surgery Azienda Ospedaliera Maggiore della Carità University of Piemonte Orientale Amedeo Avogadro, Novara, Italy.
J Craniofac Surg. 2010 Nov;21(6):2012-4. doi: 10.1097/SCS.0b013e3181f538b4.
Breast cancer continues to be the second most common cancer among women, after nonmelanoma skin cancer; in the United States, there is an average lifetime risk of 11% for developing a breast malignancy. Metastatic tumors from distant primary foci to the maxillofacial (MF) region are reported to account for only 1% of all MF malignancies, usually with grave prognosis. In the MF region, the bones more frequently involved in metastasis are the mandible, maxilla, temporal bone, frontal bone, and malar bone; the soft tissues more affected are gingiva, parotid gland, tongue, submandibular gland, and cheek. We describe a unique case of a solitary mass found in the body of the right zygoma, revealing a metastasis from breast cancer. According to the literature, the zygomatic complex is a very unusual site for metastasis; we found only 4 cases of metastatic localization from lung, rectum, liver, and uterine cancer. In MF region, oral and nasal cavity has been described as atypical sites of metastasis from breast cancer; this is to our knowledge the first recorded instance of malar metastasis from breast cancer.
乳腺癌仍然是女性中第二常见的癌症，仅次于非黑素瘤皮肤癌；在美国，患乳腺恶性肿瘤的终生平均风险为11%。据报道，远处原发性病灶转移至颌面（MF）区域的肿瘤仅占所有MF恶性肿瘤的1%，通常预后严重。在MF区域，转移中更常累及的骨骼是下颌骨、上颌骨、颞骨、额骨和颧骨；受影响更严重的软组织是牙龈、腮腺、舌、下颌下腺和颊部。我们描述了一例在右侧颧骨体发现的孤立性肿块的独特病例，结果显示为乳腺癌转移。根据文献，颧复合体是一个非常不寻常的转移部位；我们仅发现4例来自肺癌、直肠癌、肝癌和子宫癌的转移定位病例。在MF区域，口腔和鼻腔已被描述为乳腺癌转移的非典型部位；据我们所知，这是首例记录在案的乳腺癌颧骨转移病例。
