Centre des Maladies du Sein Deschênes-Fabia, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec City, QC G1S 4L8, Canada.
Breast Cancer Res Treat. 2011 Jul;128(2):563-6. doi: 10.1007/s10549-011-1453-y. Epub 2011 Mar 24.
Chemotherapy-induced alopecia is a commonly feared chemotherapy side effect and can be prevented using scalp cooling. Scalp metastasis is a rare site of recurrence. There is a question about whether or not the risk might be increased with the use of scalp cooling. Two cases of breast cancer with scalp metastases as first metastatic site are presented. The first patient presented with a scalp metastasis as first metastatic site 9 years following breast cancer chemotherapy treatments; she used scalp cooling for the adjuvant treatment. Second case presented a scalp metastasis as first metastatic site 7 years following treatments for her first cancer; overall, she used scalp cooling in only one of her six adjuvant chemotherapy cycles. Scalp metastases as the first site of recurrence are very rare entities. Scalp cooling is unlikely to have contributed in the cases presented here.
化疗引起的脱发是一种常见的化疗副作用，可以通过头皮冷却来预防。头皮转移是一种罕见的复发部位。有人怀疑头皮冷却是否会增加这种风险。本文报告了两例乳腺癌头皮转移作为首发转移部位的病例。第一个患者在乳腺癌化疗治疗 9 年后出现头皮转移作为首发转移部位；她在辅助治疗中使用了头皮冷却。第二个病例在第一次癌症治疗 7 年后出现头皮转移作为首发转移部位；总的来说，她只在六个辅助化疗周期中的一个周期中使用了头皮冷却。头皮转移作为首发转移部位是非常罕见的。在本文报告的病例中，头皮冷却不太可能起到作用。
