Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
作者信息
Ding Xia, Yan Feng, Yao Phil, Yang Zhihong, Wan Weihong, Wang Xiwei, Liu Jing, Gao Xinjiao, Abrieu Ariane, Zhu Tongge, Zhang Jiancun, Dou Zhen, Yao Xuebiao
出版信息
Cell Res. 2010 Dec;20(12):1386-9. doi: 10.1038/cr.2010.167. Epub 2010 Nov 30.
Abstract
摘要
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本文引用的文献
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Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.中心体相关蛋白-E 变构抑制剂的抗肿瘤活性。
Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5839-44. doi: 10.1073/pnas.0915068107. Epub 2010 Feb 18.
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Chromosome congression in the absence of kinetochore fibres.在没有动粒纤维的情况下染色体的汇聚。
Nat Cell Biol. 2009 Jul;11(7):832-8. doi: 10.1038/ncb1890. Epub 2009 Jun 14.
3
The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability.有丝分裂检查点激酶NEK2A调节动粒微管附着稳定性。
Oncogene. 2008 Jul 3;27(29):4107-14. doi: 10.1038/onc.2008.34. Epub 2008 Feb 25.
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Chromosomes can congress to the metaphase plate before biorientation.染色体在双定向之前可汇聚到中期板。
Science. 2006 Jan 20;311(5759):388-91. doi: 10.1126/science.1122142.
5
Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling.CENP-E介导的微管捕获使BubR1依赖的有丝分裂检查点信号沉默。
J Cell Biol. 2005 Sep 12;170(6):873-80. doi: 10.1083/jcb.200505040. Epub 2005 Sep 6.
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Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling.着丝粒与动粒：从表观遗传学到有丝分裂检查点信号传导
Cell. 2003 Feb 21;112(4):407-21. doi: 10.1016/s0092-8674(03)00115-6.
7
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint.着丝粒蛋白E在纺锤体微管与动粒的附着以及有丝分裂检查点之间建立了联系。
Nat Cell Biol. 2000 Aug;2(8):484-91. doi: 10.1038/35019518.
8
CENP-E function at kinetochores is essential for chromosome alignment.着丝粒蛋白E（CENP-E）在动粒处的功能对于染色体排列至关重要。
J Cell Biol. 1997 Dec 15;139(6):1373-82. doi: 10.1083/jcb.139.6.1373.
9
Two different microtubule-based motor activities with opposite polarities in kinetochores.动粒中两种具有相反极性的基于微管的不同运动活性。
Nature. 1991 May 16;351(6323):206-11. doi: 10.1038/351206a0.
10
CENP-E is a putative kinetochore motor that accumulates just before mitosis.着丝粒蛋白E是一种假定的动粒马达蛋白，在有丝分裂前积累。
Nature. 1992 Oct 8;359(6395):536-9. doi: 10.1038/359536a0.
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