Ginzburg A S, Onal E, Aronson R M, Schild J A, Mafee M F, Lopata M
Department of Medicine, University of Illinois Hospital, Chicago.
Chest. 1990 Jun;97(6):1496-8. doi: 10.1378/chest.97.6.1496.
A patient with Hunter syndrome and diffuse airway obstruction had daytime hypersomnolence, snoring, and alveolar hypoventilation. Polysomnography showed severe obstructive sleep apnea. In the past, all reported cases of sleep apnea in patients with mucopolysaccharidoses had been treated with tonsillectomy/adenoidectomy or tracheostomy. This patient, in whom tracheostomy would have been very difficult due to the diffuse nature of his airway involvement, was successfully treated with high pressure nasal CPAP and supplemental oxygen.
一名患有亨特综合征和弥漫性气道阻塞的患者出现日间嗜睡、打鼾和肺泡通气不足。多导睡眠图显示严重阻塞性睡眠呼吸暂停。过去，所有报道的黏多糖贮积症患者睡眠呼吸暂停病例均采用扁桃体切除术/腺样体切除术或气管切开术治疗。该患者由于气道受累的弥漫性，气管切开术会非常困难，经高压鼻持续气道正压通气（CPAP）和补充氧气成功治疗。
