Sarkar A, Roy P P, Dey S K, Dwari A K, Bandyopadhyay R, Chakraborty K, Das A
Dept. of Tuberculosis & Respiratory Medicine, Medical College, Kolkata.
J Assoc Physicians India. 2010 Jul;58:453-5.
Immature mediastinal teratoma is very rare, found in only 1% of all mediastinal teratomas. Raised serum alpha feto-protein acts as important surrogate marker for both diagnosis and follow up in such cases. Surgery and adjuvant chemotherapy are keys in the management, especially in patients older than 15 years of age. We present a 14-year-boy presenting clinico-radiologically as left sided massive pleural effusion. Raised serum marker as well as excision biopsy of the mediastinal mass following thoracotomy were indicative of a diagnosis of immature teratoma.
未成熟纵隔畸胎瘤非常罕见,仅占所有纵隔畸胎瘤的1%。血清甲胎蛋白升高是此类病例诊断和随访的重要替代标志物。手术和辅助化疗是治疗的关键,尤其是对于15岁以上的患者。我们报告一名14岁男孩,临床和放射学表现为左侧大量胸腔积液。血清标志物升高以及开胸术后纵隔肿块的切除活检提示未成熟畸胎瘤的诊断。