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第一、二颈椎骨骨样骨瘤。4 例报告。

Osteoid osteoma of the first 2 cervical vertebrae. Report of 4 cases.

机构信息

Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Neurosurg Spine. 2010 Dec;13(6):707-14. doi: 10.3171/2010.5.SPINE09297.

Abstract

Osteoid osteoma affects the spine in only 10% of cases. More than 50% of the spinal cases involve the lumbar and cervical vertebrae. Involvement of C-1 and C-2 vertebrae has previously been reported only very rarely in the published literature. The authors report 4 cases of upper cervical osteoid osteoma, 1 involving C-1 and the other 3 C-2, and they discuss different aspects of management in similar cases. The patients were 14, 17, 35, and 46 years old, and all presented with neck pain and various degrees of painful limitation of head rotation not ameliorated by ordinary analgesics. Radionuclide isotope bone scans, CT scanning, and MR imaging were helpful preoperative diagnostic modalities. The first attempt at eradication of the lesions failed in 2 cases and the lesions could be excised totally at a second approach. Postoperatively, the patients all became pain free and gained full range of neck motion. There has been no tumor recurrence and no sign of instability in short- to medium-term follow-up. Among the several etiologies mentioned for neck pain and torticollis, osteoid osteoma of the first 2 cervical vertebrae should be considered as a possible but rare cause. Even though different kinds of management have been mentioned for osteoid osteoma, resection of the lesion remains the best option for achieving a cure.

摘要

骨样骨瘤在脊柱中仅影响 10%的病例。超过 50%的脊柱病例涉及腰椎和颈椎。先前在已发表的文献中仅很少有 C-1 和 C-2 椎体受累的报道。作者报告了 4 例上颈椎骨样骨瘤,1 例累及 C-1,另 3 例累及 C-2,并讨论了类似病例的不同管理方面。患者年龄分别为 14、17、35 和 46 岁,均表现为颈痛和不同程度的疼痛性头部旋转受限,普通止痛药无效。放射性核素骨扫描、CT 扫描和磁共振成像有助于术前诊断。在 2 例患者中,第一次尝试消除病变失败,第二次尝试可完全切除病变。术后,所有患者均疼痛消失,颈部活动范围完全恢复。在短期至中期随访中,无肿瘤复发和不稳定迹象。在引起颈痛和斜颈的几种病因中,应考虑第一和第二颈椎的骨样骨瘤是一种可能但罕见的病因。尽管已经提到了多种治疗骨样骨瘤的方法,但切除病变仍然是实现治愈的最佳选择。

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