铋碘酚——它是如何起作用的？

BIPP--how does it work?

作者信息

Nigam A, Allwood M C

机构信息

Department of Otolaryngology, Addenbrooke's Hospital, Cambridge, UK.

出版信息

Clin Otolaryngol Allied Sci. 1990 Apr;15(2):173-5. doi: 10.1111/j.1365-2273.1990.tb00452.x.

DOI:10.1111/j.1365-2273.1990.tb00452.x

PMID:2112432

Abstract

The antibacterial activity of BIPP and its constituents against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa was measured by growth inhibition tests. BIPP was found to have negligible antibacterial activity. In addition, no release of iodine from BIPP was detected over a 4-week period. It is proposed that much of the evident antibacterial activity of BIPP may be a reflection of the meticulous surgical debridement that accompanies its use. In addition, BIPP makes the impregnated gauze impervious to blood and body fluids ensuring little nutrition for bacteria to thrive in its interstices.

摘要

通过生长抑制试验测定了铋碘酚（BIPP）及其成分对金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌的抗菌活性。结果发现BIPP的抗菌活性可忽略不计。此外，在4周的时间内未检测到BIPP中有碘释放。有人提出，BIPP明显的抗菌活性很大程度上可能反映了其使用过程中细致的外科清创术。此外，BIPP使浸渍纱布不透血和体液，确保细菌在其间隙中几乎没有营养来繁殖。