烧伤护理中的局部抗菌药物：第1部分 - 局部防腐剂
Topical Antimicrobials in Burn Care: Part 1-Topical Antiseptics.
作者信息
Cambiaso-Daniel Janos, Boukovalas Stafanos, Bitz Genevieve H, Branski Ludwik K, Herndon David N, Culnan Derek M
出版信息
Ann Plast Surg. 2018 Jan 9. doi: 10.1097/SAP.0000000000001297.
Abstract
Burn wounds disrupt the body's primary defense against invasion and colonization by microorganisms. Topical antimicrobials are one component in burn wound care. These agents suppress microbial growth to advantage skin cells and wound healing. Topical antimicrobials can be divided into 2 superclasses: antiseptics and antibiotics. We review the 4 main classes of topical antiseptics (emulsifiers, acids, oxidizers, and heavy metals) and antiseptic-impregnated dressings in current clinical use and address the mechanisms, as well as the advantages and disadvantages of each antiseptic for burn wound management.
摘要
烧伤创面会破坏人体抵御微生物入侵和定植的主要防线。局部抗菌药物是烧伤创面护理的一个组成部分。这些药物可抑制微生物生长，有利于皮肤细胞和创面愈合。局部抗菌药物可分为两大类：防腐剂和抗生素。我们综述了目前临床使用的4类主要局部防腐剂（乳化剂、酸类、氧化剂和重金属）以及含抗菌剂敷料，并阐述了每种防腐剂用于烧伤创面处理的作用机制、优缺点。
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