Lv Fajin, Li Qi, Liao Jingmin, Luo Tianyou, Shen Yun, Li Jialun, Zhang John, Xie Peng
Department of Radiology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Acta Neurochir Suppl. 2011;110(Pt 2):239-45. doi: 10.1007/978-3-7091-0356-2_43.
to investigate the diagnostic performance of dual-energy subtraction CTA in evaluating intracranial aneurysms by comparison with DSA.
ninety-seven patients with suspected intracranial aneurysms were included into our study and completed both 64-section dual-energy subtraction CTA and DSA examinations. Two independent readers retrospectively reviewed all subtraction CTA images in a blinded manner. Sensitivity, specificity, positive predictive value and negative predictive value of subtraction CTA and DSA were calculated on a per-patient and per-aneurysm basis.
according to the reference standard, 96 aneurysms were present in 81 patients and no aneurysm was found in 16 patients. The overall sensitivity, specificity, positive predictive value and negative predictive value of subtraction CTA on a per-aneurysm basis were 98.9, 100, 100 and 94.1%, respectively. DSA prospectively detected 88 aneurysms in 79 of 81 patients. On a per-aneurysm basis, the sensitivity, specificity, positive predictive value and negative predictive value of DSA were 91.7, 100, 100 and 66.7%, respectively.
the diagnostic accuracy of 64-section dual-energy subtraction CTA is promising in detection and characterization of intracranial aneurysms. In most cases, it may substitute for conventional DSA as the primary imaging method in the diagnostic work-up of intracranial aneurysms.
通过与数字减影血管造影（DSA）比较，探讨双能量减影CT血管造影（CTA）在评估颅内动脉瘤中的诊断性能。
97例疑似颅内动脉瘤患者纳入本研究，均完成64层双能量减影CTA和DSA检查。两名独立阅片者以盲法回顾性分析所有减影CTA图像。分别计算减影CTA和DSA在每位患者及每个动脉瘤基础上的敏感性、特异性、阳性预测值和阴性预测值。
根据参考标准，81例患者中发现96个动脉瘤，16例患者未发现动脉瘤。减影CTA在每个动脉瘤基础上的总体敏感性、特异性、阳性预测值和阴性预测值分别为98.9%、100%、100%和94.1%。DSA前瞻性检测到81例患者中79例有88个动脉瘤。在每个动脉瘤基础上，DSA的敏感性、特异性、阳性预测值和阴性预测值分别为91.7%、100%、100%和66.7%。
64层双能量减影CTA在颅内动脉瘤的检测和特征描述方面诊断准确性良好。在大多数情况下，它可替代传统DSA作为颅内动脉瘤诊断检查的主要成像方法。
