Department of Abdominal Surgery, Clinical Center of Montenegro, Podgorica, Montenegro.
BMC Gastroenterol. 2010 Dec 2;10:141. doi: 10.1186/1471-230X-10-141.
This study was designed to determine the role of primary repair and to investigate the possibility of expanding indications for primary repair of colon injuries using nonselective approach.
Two groups of patients were analyzed. Retrospective (RS) group included 30 patients managed by primary repair or two stage surgical procedure according to criteria published by Stone (S/F) and Flint (Fl). In this group 18 patients were managed by primary repair. Prospective (PR) group included 33 patients with primary repair as a first choice procedure. In this group, primary repair was performed in 30 cases.
Groups were comparable regarding age, sex, and indexes of trauma severity. Time between injury and surgery was shorter in PR group, (1.3 vs. 3.1 hours). Stab wounds were more frequent in PR group (9:2), and iatrogenic lesions in RS group (6:2). Associated injuries were similar, as well as segmental distribution of colon injuries. S/F criteria and Flint grading were similar.In RS group 15 primary repairs were successful, while in two cases relaparotomy and colostomy was performed due to anastomotic leakage. One patient died. In PR group, 25 primary repairs were successful, with 2 immediate and 3 postoperative (7-10 days) deaths, with no evidence of anastomotic leakage.
Results of this study justify more liberal use of primary repair in early management of colon injuries.
Current Controlled Trials ISRCTN94682396.
本研究旨在确定一期修复的作用,并探讨使用非选择性方法扩大一期修复结肠损伤适应证的可能性。
分析了两组患者。回顾性(RS)组包括 30 例根据 Stone(S/F)和 Flint(Fl)标准接受一期修复或两期手术治疗的患者。该组中有 18 例接受了一期修复。前瞻性(PR)组包括 33 例将一期修复作为首选治疗方法的患者。该组中有 30 例患者进行了一期修复。
两组患者在年龄、性别和创伤严重程度指标方面具有可比性。PR 组的手术时间更短(1.3 小时 vs. 3.1 小时)。PR 组中锐器伤更为常见(9 例 vs. 2 例),而 RS 组中医源性损伤更为常见(6 例 vs. 2 例)。合并伤相似,结肠损伤的节段分布也相似。S/F 标准和 Flint 分级相似。RS 组中有 15 例一期修复成功,2 例因吻合口漏而再次剖腹和结肠造口术。1 例死亡。PR 组中,25 例一期修复成功,2 例即刻死亡,3 例术后(7-10 天)死亡,无吻合口漏的证据。
本研究结果证明,在早期处理结肠损伤时,更应广泛应用一期修复。
当前对照试验 ISRCTN94682396。