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结肠损伤的一期修复:非选择性方法的临床研究。

Primary repair of colon injuries: clinical study of nonselective approach.

机构信息

Department of Abdominal Surgery, Clinical Center of Montenegro, Podgorica, Montenegro.

出版信息

BMC Gastroenterol. 2010 Dec 2;10:141. doi: 10.1186/1471-230X-10-141.

DOI:10.1186/1471-230X-10-141
PMID:21126337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3014882/
Abstract

BACKGROUND

This study was designed to determine the role of primary repair and to investigate the possibility of expanding indications for primary repair of colon injuries using nonselective approach.

METHODS

Two groups of patients were analyzed. Retrospective (RS) group included 30 patients managed by primary repair or two stage surgical procedure according to criteria published by Stone (S/F) and Flint (Fl). In this group 18 patients were managed by primary repair. Prospective (PR) group included 33 patients with primary repair as a first choice procedure. In this group, primary repair was performed in 30 cases.

RESULTS

Groups were comparable regarding age, sex, and indexes of trauma severity. Time between injury and surgery was shorter in PR group, (1.3 vs. 3.1 hours). Stab wounds were more frequent in PR group (9:2), and iatrogenic lesions in RS group (6:2). Associated injuries were similar, as well as segmental distribution of colon injuries. S/F criteria and Flint grading were similar.In RS group 15 primary repairs were successful, while in two cases relaparotomy and colostomy was performed due to anastomotic leakage. One patient died. In PR group, 25 primary repairs were successful, with 2 immediate and 3 postoperative (7-10 days) deaths, with no evidence of anastomotic leakage.

CONCLUSIONS

Results of this study justify more liberal use of primary repair in early management of colon injuries.

TRIAL REGISTRATION

Current Controlled Trials ISRCTN94682396.

摘要

背景

本研究旨在确定一期修复的作用,并探讨使用非选择性方法扩大一期修复结肠损伤适应证的可能性。

方法

分析了两组患者。回顾性(RS)组包括 30 例根据 Stone(S/F)和 Flint(Fl)标准接受一期修复或两期手术治疗的患者。该组中有 18 例接受了一期修复。前瞻性(PR)组包括 33 例将一期修复作为首选治疗方法的患者。该组中有 30 例患者进行了一期修复。

结果

两组患者在年龄、性别和创伤严重程度指标方面具有可比性。PR 组的手术时间更短(1.3 小时 vs. 3.1 小时)。PR 组中锐器伤更为常见(9 例 vs. 2 例),而 RS 组中医源性损伤更为常见(6 例 vs. 2 例)。合并伤相似,结肠损伤的节段分布也相似。S/F 标准和 Flint 分级相似。RS 组中有 15 例一期修复成功,2 例因吻合口漏而再次剖腹和结肠造口术。1 例死亡。PR 组中,25 例一期修复成功,2 例即刻死亡,3 例术后(7-10 天)死亡,无吻合口漏的证据。

结论

本研究结果证明,在早期处理结肠损伤时,更应广泛应用一期修复。

试验注册

当前对照试验 ISRCTN94682396。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44db/3014882/1c50af1eedc7/1471-230X-10-141-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44db/3014882/1c50af1eedc7/1471-230X-10-141-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44db/3014882/1c50af1eedc7/1471-230X-10-141-1.jpg

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本文引用的文献

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New trends in the management of colonic trauma.结肠创伤管理的新趋势。
Injury. 2005 Sep;36(9):1011-5. doi: 10.1016/j.injury.2004.11.020.
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Canadian Association of General Surgeons evidence based reviews in surgery. 12. Primary repair for penetrating colon injuries.加拿大普通外科医生协会外科学循证综述。12. 穿透性结肠损伤的一期修复
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Colon injuries: new perspectives.结肠损伤:新视角
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The morbidity of penetrating colon injury.结肠穿透伤的发病率。
Injury. 2003 Jan;34(1):41-6. doi: 10.1016/s0020-1383(02)00090-6.
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Handsewn versus stapled anastomosis in penetrating colon injuries requiring resection: a multicenter study.在需要进行切除的穿透性结肠损伤中,手工缝合与吻合器吻合的比较:一项多中心研究。
J Trauma. 2002 Jan;52(1):117-21. doi: 10.1097/00005373-200201000-00020.
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Evolving concepts in the management of colonic injury.结肠损伤管理的演变概念。
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Penetrating colon injuries requiring resection: diversion or primary anastomosis? An AAST prospective multicenter study.需要切除的穿透性结肠损伤:转流术还是一期吻合术?美国创伤外科学会前瞻性多中心研究。
J Trauma. 2001 May;50(5):765-75. doi: 10.1097/00005373-200105000-00001.
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