成功使用达托霉素治疗新生儿耐甲氧西林金黄色葡萄球菌菌血症。
Successful treatment of meticillin-resistant Staphylococcus aureus bacteraemia in a neonate using daptomycin.
机构信息
Department of Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
Department of Child Health, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.
出版信息
J Med Microbiol. 2011 Mar;60(Pt 3):381-383. doi: 10.1099/jmm.0.027235-0. Epub 2010 Dec 2.
Daptomycin is licensed for the management of Staphylococcus aureus infections in adults, including those caused by meticillin-resistant S. aureus (MRSA). Few data exist on paediatric use or dose guidance in neonates. We report the case of a neonate with MRSA bacteraemia successfully managed with daptomycin. Dose requirements were substantially higher than those recommended for adults.
达托霉素被批准用于治疗成人金黄色葡萄球菌感染，包括耐甲氧西林金黄色葡萄球菌（MRSA）引起的感染。关于新生儿的儿科使用或剂量指导的数据很少。我们报告了一例 MRSA 菌血症新生儿成功使用达托霉素治疗的病例。剂量需求远高于成人推荐剂量。
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