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达托霉素用于治疗极早早产儿心内膜炎——结局与展望

Daptomycin for Treatment of Endocarditis in an Extremely Preterm Neonate-Outcome and Perspectives.

作者信息

Minotti Chiara, Zuccon Ilaria, Priante Elena, Bonadies Luca, Di Chiara Costanza, Donà Daniele, Baraldi Eugenio, Costenaro Paola

机构信息

Department of Women's and Children's Health, University of Padua, Via Giustiniani 2, 35128 Padua, Italy.

Neonatal Intensive Care Unit, Department of Women's and Children's Health, University Hospital of Padua, Via Giustiniani 2, 35128 Padua, Italy.

出版信息

Children (Basel). 2022 Mar 24;9(4):457. doi: 10.3390/children9040457.

Abstract

With a considerable morbidity and mortality burden, infective endocarditis still represents a challenge for clinicians. This is a case of persistent endocarditis in an extremely preterm newborn. The infection, initially treated with vancomycin, was successfully cured with daptomycin. Its use was safe and effective, ensuring a complete remission without adverse effects.

摘要

感染性心内膜炎具有相当高的发病率和死亡率负担,仍然是临床医生面临的一项挑战。这是一例极早早产儿持续性心内膜炎的病例。该感染最初用万古霉素治疗,最终用达托霉素成功治愈。达托霉素的使用安全有效,确保了完全缓解且无不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bdf/9030184/bc7f7b7b6b58/children-09-00457-g001.jpg

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