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伴有脾脏钙化的腹腔疾病。

Celiac disease with splenic calcifications.

机构信息

Department of Pediatrics, Lady Hardinge Medical College, New Delhi, India.

出版信息

Indian J Pediatr. 2011 Jun;78(6):740-2. doi: 10.1007/s12098-010-0293-9. Epub 2010 Dec 3.

DOI:10.1007/s12098-010-0293-9
PMID:21128017
Abstract

Celiac disease is an immune mediated enteropathy due to irreversible gluten sensitivity. It has protean manifestations involving gastrointestinal (GI) as well as non GI manifestations. Calcifications in the cerebral cortex are well defined entity in celiac disease known as CEC syndrome (Celiac disease, Epilepsy and Cerebral Calcification). Calcification has not been described in any other organ. Splenic calcifications are a rare manifestation in childhood. The authors are reporting a case of celiac disease with multiple foci of calcification in the spleen without evidence of cerebral calcification.

摘要

乳糜泻是一种由不可逆转的麸质敏感性引起的免疫介导性肠病。它有多种表现形式,涉及胃肠道(GI)和非胃肠道表现。大脑皮层钙化是乳糜泻中的一种明确实体,称为 CEC 综合征(乳糜泻、癫痫和大脑钙化)。在任何其他器官中都没有描述过钙化。脾钙化在儿童中是一种罕见的表现。作者报告了一例乳糜泻病例,脾内有多个钙化灶,无大脑钙化证据。

相似文献

1
Celiac disease with splenic calcifications.伴有脾脏钙化的腹腔疾病。
Indian J Pediatr. 2011 Jun;78(6):740-2. doi: 10.1007/s12098-010-0293-9. Epub 2010 Dec 3.
2
Case report: hepatic and splenic calcification due to amyloid.病例报告:淀粉样变性所致肝脾钙化
Clin Radiol. 1991 Jul;44(1):60-1. doi: 10.1016/s0009-9260(05)80230-2.
3
[Cerebral calcifications: a clue for a diagnostic process in a nonspecific clinical case].[脑钙化:非特异性临床病例诊断过程中的一条线索]
An Med Interna. 2006 Mar;23(3):127-9. doi: 10.4321/s0212-71992006000300007.
4
Hepatosplenic antracosilicosis: a rare cause of splenic calcifications.肝脾炭疽矽肺:脾钙化的罕见病因。
Eur Radiol. 2001;11(7):1184-6. doi: 10.1007/s003300000717.
5
Splenic calcification in sickle cell anemia.镰状细胞贫血中的脾脏钙化。
Am J Med Sci. 1973 Jun;265(6):495-9. doi: 10.1097/00000441-197306000-00009.
6
Coeliac disease, epilepsy and cerebral calcifications.乳糜泻、癫痫和脑钙化。
Brain Dev. 2005 Apr;27(3):189-200. doi: 10.1016/j.braindev.2004.05.003.
7
Images in clinical medicine. Occipital calcification and celiac disease.临床医学影像。枕部钙化与乳糜泻。
N Engl J Med. 2014 Apr 17;370(16):e26. doi: 10.1056/NEJMicm1311406.
8
Images in clinical medicine. Splenic calcification.临床医学影像。脾钙化。
N Engl J Med. 2011 Sep 15;365(11):1042. doi: 10.1056/NEJMicm1100222.
9
[Epilepsy, cerebral calcifications and celiac disease].[癫痫、脑钙化与乳糜泻]
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A Case of Celiac Disease, Epilepsy, and Cerebral Calcifications With Temporal Lobe Epilepsy.一例伴有颞叶癫痫的乳糜泻、癫痫和脑钙化病例。
WMJ. 2015 Jun;114(3):116-7; quiz 118.

引用本文的文献

1
Diffuse Calcifications of the Spleen in a Woman with Systemic Lupus Erythematosus.一名系统性红斑狼疮女性患者脾脏的弥漫性钙化
Case Rep Med. 2015;2015:414102. doi: 10.1155/2015/414102. Epub 2015 Aug 17.

本文引用的文献

1
Liver involvement in celiac disease.乳糜泻中的肝脏受累情况。
Indian J Pediatr. 2006 Sep;73(9):809-11. doi: 10.1007/BF02790391.
2
Unusual manifestations of celiac disease.乳糜泻的不寻常表现。
Indian J Pediatr. 2006 Aug;73(8):711-6. doi: 10.1007/BF02898450.
3
Prevalence of celiac disease among school children in Punjab, North India.印度北部旁遮普邦学童中的乳糜泻患病率。
J Gastroenterol Hepatol. 2006 Oct;21(10):1622-5. doi: 10.1111/j.1440-1746.2006.04281.x.
4
Coeliac disease, epilepsy and cerebral calcifications.乳糜泻、癫痫和脑钙化。
Brain Dev. 2005 Apr;27(3):189-200. doi: 10.1016/j.braindev.2004.05.003.
5
Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.儿童乳糜泻诊断与治疗指南:北美儿科胃肠病、肝病和营养学会的建议
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Epilepsy, occipital calcifications, and oligosymptomatic celiac disease in childhood.儿童期癫痫、枕部钙化与轻症乳糜泻
J Child Neurol. 2002 Nov;17(11):800-6. doi: 10.1177/08830738020170110801.
7
Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier.一名患有癫痫、脑钙化、药物性系统性红斑狼疮及肠道叶酸吸收不良且伴有叶酸跨血脑屏障转运受损的儿童的潜在性腹腔疾病。
Eur J Pediatr. 2001 May;160(5):288-92. doi: 10.1007/s004310100728.
8
[Epilepsy, bi-occipital calcifications and celiac disease].[癫痫、双侧枕叶钙化与乳糜泻]
Rev Neurol (Paris). 2001 Jan;157(1):116-8.
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Celiac disease in India.印度的乳糜泻
Indian J Pediatr. 1999;66(1 Suppl):S16-20.
10
Asp57-negative HLA DQ beta chain and DQA1*0501 allele are essential for the onset of DQw2-positive and DQw2-negative coeliac disease.天冬氨酸57阴性的HLA DQβ链和DQA1*0501等位基因对于DQw2阳性和DQw2阴性乳糜泻的发病至关重要。
Clin Exp Immunol. 1993 Jan;91(1):153-6. doi: 10.1111/j.1365-2249.1993.tb03371.x.