Hypertension Center, Cedars-Sinai Heart Institute, Los Angeles, CA 90048, USA.
Curr Cardiol Rep. 2011 Feb;13(1):86-92. doi: 10.1007/s11886-010-0156-z.
Invasive device-based therapies for drug-resistant hypertension are undergoing active clinical investigation. The two approaches are 1) permanent implantation of a carotid baroreceptor pacemaker and 2) radiofrequency catheter ablation of the renal nerves. Both are designed to reduce the sympathetic nervous system component of drug-resistant hypertension. Several excellent comprehensive articles have reviewed each of these devices separately. In contrast, this brief article aims to provide a conceptual framework for evaluating the premise, promise, and potential limitations of both invasive antihypertensive therapies.
基于侵袭性器械的药物抵抗性高血压治疗方法正在积极的临床研究中。这两种方法是 1）颈动脉压力感受器起搏器的永久性植入，和 2）肾神经的射频导管消融。两者旨在降低药物抵抗性高血压的交感神经系统成分。有几篇优秀的综合文章分别对这些设备进行了综述。相比之下，这篇简短的文章旨在为评估这两种侵袭性降压治疗的前提、前景和潜在局限性提供一个概念框架。
