Department of Psychiatry, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
CNS Drugs. 2011 Jan;25(1):17-36. doi: 10.2165/11538450-000000000-00000.
Remission should be the goal of attention-deficit hyperactivity disorder (ADHD) treatment. However, there is no universally accepted definition of remission in ADHD, although clinical studies use a number of criteria. This article examines current research into the concept of remission in ADHD by reviewing the literature for definition and achievement of remission in children and adults with ADHD. Results demonstrate that the concept of remission in ADHD has been proposed by several study groups, using thresholds of validated rating scales to indicate syndromic, symptomatic and functional remission. Several studies have demonstrated the achievement of remission in ADHD children utilizing methylphenidate delivered by an osmotic, controlled-release formulation (OROS®) and atomoxetine. However, none has defined a time period over which these criteria must be met for an individual with ADHD to be considered 'in remission'. Standardized remission criteria in ADHD will provide a tool for assessing the effectiveness of treatments for ADHD, and raise treatment standards.
缓解应成为注意力缺陷多动障碍（ADHD）治疗的目标。然而，ADHD 缓解并没有被普遍接受的定义，尽管临床研究使用了许多标准。本文通过综述儿童和成人 ADHD 缓解的定义和实现，探讨 ADHD 缓解的概念。结果表明，ADHD 缓解的概念已经被几个研究小组提出，使用验证过的评定量表的阈值来表示综合征、症状和功能缓解。几项研究已经证明，使用渗透压控制释放制剂（OROS®）和托莫西汀治疗 ADHD 儿童可以达到缓解。然而，尚无研究定义个体必须满足这些标准的时间段，以将其视为“缓解”。ADHD 缓解的标准化标准将为评估 ADHD 治疗的有效性提供工具，并提高治疗标准。
