长效硝酸盐递送系统的研发。
Development of long-acting nitrate delivery systems.
作者信息
Jonsson U E
机构信息
Pharmaceutical Research and Development, AB Hässle, Mölndal, Sweden.
出版信息
Eur J Clin Pharmacol. 1990;38 Suppl 1:S15-9. doi: 10.1007/BF01417560.
PMID:2113000
Abstract
In this paper pharmaceutical and biopharmaceutical aspects on the development of long-acting nitrate delivery systems are reviewed. Basic considerations and requirements are also discussed. Recent product development activities are presented, with an emphasis on nitroglycerin in transdermal form and oral isosorbide-5-mononitrate controlled-release formulations.
摘要
本文综述了长效硝酸盐给药系统开发中的药学和生物药学方面。还讨论了基本考虑因素和要求。介绍了近期的产品开发活动，重点是透皮形式的硝酸甘油和口服5-单硝酸异山梨酯控释制剂。
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