[果蝇基因组中具有端粒定位的重复序列家族：特性与多态性]
[A family of repeated sequences in Drosophila genome with telomeric localization: properties and polymorphism].
作者信息
Danilevskaia O N, Kurenova E V, Leĭbovich B A, Bass I A, Pavlova M N
出版信息
Genetika. 1990 Mar;26(3):474-84.
PMID:2113022
Abstract
The previously cloned Drosophila genome fragment Dm665 (2.4 kb) hybridizing with telomers on polytene chromosomes is a representative of the family of repeats, a part of which being organized in tandem clusters. The repeats are not transcribed in cell culture, are species-specific and represented in 200-250 copies per haploid genome. In natural and laboratory Drosophila lines polymorphism has been revealed with regard to homology with Dm665 in the telomeres.
摘要
先前克隆的与多线染色体上的端粒杂交的果蝇基因组片段Dm665（2.4 kb）是重复序列家族的一个代表，其中一部分以串联簇的形式组织。这些重复序列在细胞培养中不转录，具有物种特异性，每个单倍体基因组中有200 - 250个拷贝。在天然和实验室果蝇品系中，已发现端粒与Dm665的同源性存在多态性。
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