General Medicine Unit, Massachusetts General Hospital, Boston, MA 02114, USA.
Prev Med. 2011 Feb;52(2):164-6. doi: 10.1016/j.ypmed.2010.11.023. Epub 2010 Dec 3.
In a cohort of employees participating in a worksite nutrition and physical activity program, we compared program completion and changes in cardiovascular risk factors by baseline body mass index.
In 2007, 774 employees enrolled in a 10 week program at a hospital in Boston, Massachusetts. Program completion and change in weight, cholesterol, and blood pressure were compared between obese (body mass index≥30), overweight (body mass index=25-29.9), and normal weight (body mass index<25) participants.
At baseline, 63% were obese or overweight and had higher blood pressure and cholesterol compared to normal weight participants. Program completion was 82% and did not differ by body mass index. Mean weight loss was 1.9 kg at end of program (p<0.001) and 0.4 kg at 1 year (p=0.002). At end of program, participants with body mass index≥30 lost 3.0% body weight vs. 2.7% for body mass index=25-29.9 and 1.7% for body mass index<25 (p<0.001), but weight loss at 1 year did not differ by body mass index. Mean cholesterol and blood pressure were lower at end of program and 1 year (all, p<0.005) but did not differ by body mass index.
Worksite programs can successfully initiate cardiovascular risk reduction among employees, but more intensive interventions are needed to make significant improvements in the health of higher risk obese employees.
在参与工作场所营养和体育活动计划的员工队列中，我们比较了根据基线体重指数（BMI）完成计划和心血管风险因素变化的情况。
2007 年，马萨诸塞州波士顿一家医院的 774 名员工参加了一项为期 10 周的计划。比较了肥胖（BMI≥30）、超重（BMI=25-29.9）和正常体重（BMI<25）参与者之间的计划完成情况和体重、胆固醇和血压的变化。
基线时，63%的参与者超重或肥胖，且血压和胆固醇水平高于正常体重参与者。计划完成率为 82%，与 BMI 无关。计划结束时平均体重减轻 1.9 公斤（p<0.001），1 年后减轻 0.4 公斤（p=0.002）。在计划结束时，BMI≥30 的参与者体重减轻了 3.0%，而 BMI=25-29.9 的参与者体重减轻了 2.7%，BMI<25 的参与者体重减轻了 1.7%（p<0.001），但 1 年后的体重减轻与 BMI 无关。计划结束和 1 年后，胆固醇和血压均值均降低（均 p<0.005），但与 BMI 无关。
工作场所计划可以成功地启动员工的心血管风险降低，但需要更强化的干预措施，才能显著改善高风险肥胖员工的健康状况。
