Department of Rheumatology, Lund University, Lund, Sweden.
Scand J Rheumatol. 2013;42(4):317-24. doi: 10.3109/03009742.2012.756928. Epub 2013 Feb 27.
To translate the visual analogue scales (VAS) in the Scleroderma Health Assessment Questionnaire (SSc HAQ) and the Cochin Hand Function Scale (CHFS) and to examine the reliability and validity of the Swedish versions of the instruments.
The reproducibility, internal consistency, acceptability, and validity of the instruments were evaluated. Eighty-three consecutive patients participated in the evaluation of the SSc HAQ and 56 in the CHFS. Sixty-six per cent fulfilled the criteria for limited systemic sclerosis (lcSSc) and 29% for diffuse systemic sclerosis (dcSSc). The patients were assessed regarding disease parameters, hand involvement, and quality of life, the latter using the 36-item short form health survey (SF-36).
The reproducibility in the HAQ Disability Index (HAQ-DI), the VAS of pulmonary, digital ulcer, and overall disease severity, and in the CHFS was good (intra-class correlation coefficients, ICCs ≥ 0.75). The internal consistency was high in the HAQ-DI and the CHFS but lower in the VAS. The HAQ-DI showed higher correlations coefficients with physical-related scores in the SF-36 (rs = -0.600) than with mental-related dimensions (rs = -0.235). All VAS showed significant correlation with the item for general health (p < 0.05). The CHFS showed high correlation to hand-related items in the HAQ (rs = 0.858) and moderate correlation to the physical summary score in SF-36 (rs = -0.521). The instruments could not discriminate between lcSSc and dcSSc, although significant correlations between the CHFS and hand involvement (p < 0.05) indicate the ability of the CHFS to discriminate between mild and severe hand involvement.
The Swedish version of the SSc HAQ and the CHFS meet the requirements of reproducibility and concurrent validity. More studies are needed to examine the capacity of these instruments to discriminate between disease severities.
翻译系统性硬化症健康评估问卷（SSc HAQ）和科钦手功能量表（CHFS）中的视觉模拟量表（VAS），并检验这些工具的瑞典版本的可靠性和有效性。
评估工具的再现性、内部一致性、可接受性和有效性。83 例连续患者参与 SSc HAQ 评估，56 例参与 CHFS 评估。66%的患者符合局限性系统性硬化症（lcSSc）标准，29%的患者符合弥漫性系统性硬化症（dcSSc）标准。评估患者的疾病参数、手部受累情况和生活质量，后者使用 36 项简短健康调查（SF-36）。
HAQ 残疾指数（HAQ-DI）、肺部 VAS、数字溃疡 VAS 和总体疾病严重程度 VAS 以及 CHFS 的再现性良好（组内相关系数 ICC≥0.75）。HAQ-DI 和 CHFS 的内部一致性较高，但 VAS 的内部一致性较低。HAQ-DI 与 SF-36 中与身体相关的评分（rs=-0.600）的相关性高于与心理相关维度（rs=-0.235）的相关性。所有 VAS 均与一般健康项目呈显著相关性（p<0.05）。CHFS 与 HAQ 中与手部相关的项目相关性较高（rs=0.858），与 SF-36 中身体综合评分的相关性中等（rs=-0.521）。这些工具无法区分 lcSSc 和 dcSSc，尽管 CHFS 与手部受累之间存在显著相关性（p<0.05），表明 CHFS 有能力区分轻度和重度手部受累。
SSc HAQ 和 CHFS 的瑞典版本满足再现性和同时有效性的要求。需要进一步研究这些工具区分疾病严重程度的能力。
