Am J Gastroenterol. 2010 Dec;105(12):2586-7. doi: 10.1038/ajg.2010.365.
Computed tomographic (CT) colonography (CTC) represents an alternative to optical colonoscopy for colorectal cancer screening. However, diminutive polyps (≤ 5 mm) are not routinely reported for CTC. An observational study comparing the rates of recovery of subcentimeter adenomas in average-risk patients between two screening strategies, CTC and optical colonoscopy, found that the colonoscopy group had a four and a half-fold greater recovery rate of diminutive adenomas. Although the study was not randomized, the results highlight the difference between the two screening strategies. Because of incomplete understanding of the natural history of diminutive adenomas, further study is needed to determine the long-term impact of the use of CTC for colorectal cancer screening.
计算机断层扫描（CT）结肠成像（CTC）是结直肠癌筛查的结肠镜检查替代方法。然而，CTC 通常不会报告微小息肉（≤5 毫米）。一项观察性研究比较了两种筛查策略（CTC 和光学结肠镜检查）在平均风险患者中亚厘米大小腺瘤的检出率，发现结肠镜组检出微小腺瘤的比例高出四倍半。尽管该研究并非随机，但结果突出了两种筛查策略之间的差异。由于对微小腺瘤的自然史了解不完整，需要进一步研究来确定 CTC 在结直肠癌筛查中的应用对长期的影响。
