Mathur Sachin, Visvanathan Mahesh, Svojanovsky Stan, Yoo Byunggil, Srinivas Adagarla B, Lushington Gerald H, Smith Peter G
School of Computing and Engineering, University of Missouri-Kansas City, MO 64110, USA.
Open Bioinforma J. 2009 Jan 1;3:26-30. doi: 10.2174/1875036200903010026.
We have developed the web based tool GOAPhAR (Gene Ontology, Annotations and Pathways for Array Research), that integrates information from disparate sources regarding gene annotations, protein annotations, identifiers associated with probe sets, functional pathways, protein interactions, Gene Ontology, publicly available microarray datasets and tools for statistically validating clusters in microarray data. Genes of interest can be input as Affymetrix probe identifiers, Genbank, or Unigene identifiers for human, mouse or rat genomes. Results are provided in a user friendly interface with hyperlinks to the sources of information.
我们开发了基于网络的工具GOAPhAR(用于阵列研究的基因本体、注释和通路),该工具整合了来自不同来源的有关基因注释、蛋白质注释、与探针集相关的标识符、功能通路、蛋白质相互作用、基因本体、公开可用的微阵列数据集以及用于统计验证微阵列数据中聚类的工具等信息。感兴趣的基因可以作为Affymetrix探针标识符、Genbank或人类、小鼠或大鼠基因组的Unigene标识符输入。结果通过用户友好的界面提供,并带有指向信息来源的超链接。