Povlsen J V, Rasmussen A, Hansen H E, Fjeldborg O, Kissmeyer-Nielsen F, Madsen M
Department of Clinical Immunology, University Hospital, Aarhus, Denmark.
Nephrol Dial Transplant. 1990;5(2):148-51. doi: 10.1093/ndt/5.2.148.
Of 1041 renal allograft transplantations performed in our centre, 142 (13.6%) were carried out with ABO-minor-incompatible kidneys. Anti-recipient ABO antibodies were found in two of 34 patients treated with cyclosporin. These two cases of severe but self-limited haemolysis due to anti-A1 and anti-B, respectively, are reported in detail. Among 108 azathioprine-treated patients no evidence of the disorder was found. The condition should be suspected in any recipient with an unexpected reduction in haematrocrit or other signs of haemolysis after ABO-minor-incompatible organ transplantation.
在我们中心进行的1041例肾移植手术中，142例（13.6%）是使用ABO次要不相容肾脏进行的。在34例接受环孢素治疗的患者中，有2例发现了抗受者ABO抗体。分别详细报告了这2例因抗A1和抗B导致的严重但自限性溶血病例。在108例接受硫唑嘌呤治疗的患者中，未发现该病症的证据。在ABO次要不相容器官移植后，任何出现意外血细胞比容降低或其他溶血迹象的受者都应怀疑患有该病症。
