School of Pharmaceutical Sciences, University of Shizuoka and Global COE Program, 52-1 Yada, Suruga-ku, Shizuoka-shi, Shizuoka 422-8526, Japan.
Chem Commun (Camb). 2011 Feb 14;47(6):1794-6. doi: 10.1039/c0cc03676e. Epub 2010 Dec 3.
A concise synthesis of APDOEGCg (3) was accomplished. Due to the reactivity of its amine group, the compound could be easily converted to the fluorescein probe 21 and immunogen probe 22 efficiently. We then demonstrated the usefulness of the probes for imaging studies and the generation of antibodies.
成功地对 APDOEGCg(3)进行了简洁的合成。由于其胺基的反应性,该化合物可以很容易地转化为荧光探针 21 和免疫原探针 22。然后,我们展示了这些探针在成像研究和抗体生成中的有用性。