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双水杨醛缩 4(N)-乙基硫代氨基脲合钌(III)三苯基膦的合成、结构与生物评价。

Synthesis, structure and biological evaluation of bis salicylaldehyde-4(N)-ethylthiosemicarbazone ruthenium(iii) triphenylphosphine.

机构信息

Department of Chemistry, Bharathiar University, Coimbatore, 641 046, India.

出版信息

Metallomics. 2011 Jan;3(1):42-8. doi: 10.1039/c0mt00062k. Epub 2010 Dec 6.

DOI:10.1039/c0mt00062k
PMID:21132183
Abstract

Bis salicylaldehyde-4(N)-ethylthiosemicarbazone ruthenium(iii) triphenylphosphine [Ru(Sal-etsc)(H-Sal-etsc)(PPh(3))] was synthesized and structurally characterized by spectral and X-ray crystallographic studies and it showed 100% inhibition on the DPPH radical. It also exhibited a significant lymphocyte activity and inhibitory effect on the lung carcinoma A549 cell.

摘要

双水杨醛缩 4(N)-乙基硫代半卡巴腙钌(III)三苯基膦[Ru(Sal-etsc)(H-Sal-etsc)(PPh(3))]通过光谱和 X 射线晶体学研究进行了合成和结构表征,对 DPPH 自由基表现出 100%的抑制作用。它还表现出显著的淋巴细胞活性和对肺癌 A549 细胞的抑制作用。

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