Radiation Oncology Department, Oncology Institute of Southern Switzerland, Switzerland.
Crit Rev Oncol Hematol. 2012 Dec;84 Suppl 1:e70-4. doi: 10.1016/j.critrevonc.2010.11.002. Epub 2010 Dec 4.
Post-mastectomy RT decreases the rate of locoregional recurrences of about 70% in all patients irrespective of age, tumor characteristics or systemic therapy. Post-mastectomy RT has to be proposed, moreover when locoregional lymph nodes are part of the PTV, if an optimal coverage of the PTV and a satisfactory sparing of the OAR could be obtained. Due to the results of meta-analysis, consensus conferences and randomized trials the long-term efficacy of RT in decreasing the risk of LRF is well established and the vast majority of women, treated with mastectomy, will benefit from it.
术后放疗可使所有患者局部区域复发率降低约 70%，无论年龄、肿瘤特征或全身治疗如何。术后放疗应被提出，特别是当局部区域淋巴结是 PTV 的一部分时，如果能够获得 PTV 的最佳覆盖和 OAR 的满意保护。由于荟萃分析、共识会议和随机试验的结果，放疗在降低 LRF 风险方面的长期疗效已得到充分证实，接受乳房切除术治疗的绝大多数女性将从中受益。
