Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Acta Pharm. 2010 Sep;60(3):339-48. doi: 10.2478/v10007-010-0028-5.
Mucilage extracted from Plantago psyllium seeds was evaluated for inertness and safety parameters. The suitability of psyllium mucilage for a pharmaceutical binder was assessed in paracetamol tablets. Properties of the granules prepared using different concentrations of psyllium mucilage was compared with PVP and tragacanth. Psyllium mucilage at 5 % (m/m) was found to be comparable with 3 % (m/m) of PVP. Investigated paracetamol tablets indicated that psyllium mucilage can retard the drug release.
车前草种籽中提取的黏胶被评估为惰性和安全性参数。车前草黏胶作为一种药用黏合剂的适用性在对乙酰氨基酚片中进行了评估。使用不同浓度的车前草黏胶制备颗粒的性质与 PVP 和黄蓍胶进行了比较。发现 5%（m/m）的车前草黏胶与 3%（m/m）的 PVP 相当。所研究的对乙酰氨基酚片表明，车前草黏胶可以延缓药物释放。
