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临床问题。关节内注射类固醇激素会影响糖尿病患者的血糖控制吗?

Clinical inquiries. Do intra-articular steroid injections affect glycemic control in patients with diabetes?

作者信息

Kallock Erin, Neher Jon O, Safranek Sarah

机构信息

Valley Family Medicine Residency, Renton, WA, USA.

出版信息

J Fam Pract. 2010 Dec;59(12):709-10.

PMID:21135928
Abstract

Yes, but the clinical importance is minimal. A single intra-articular steroid injection into the knee produces acute hyperglycemia for 2 or 3 days in patients with diabetes who otherwise have good glucose control (strength of recommendation [SOR]: B, small cohort studies). Intra-articular steroid injections into the shoulder may briefly raise postprandial (but not mean) glucose levels with larger and repeated doses (SOR: C, extrapolated from heterogeneous and mixed cohort studies).

摘要

是的,但临床意义极小。对于血糖控制良好的糖尿病患者,膝关节单次关节腔内注射类固醇会导致2至3天的急性高血糖(推荐强度[SOR]:B,小型队列研究)。肩部关节腔内注射类固醇,剂量较大且重复注射时,可能会短暂提高餐后(而非平均)血糖水平(SOR:C,从异质性和混合队列研究推断得出)。

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