Herink Ann-Kristin, Köthe Lars, Girndt Matthias, Keysser Gernot
Universitätsklinik und Poliklinik für Innere Medizin II, Universitätsklinikum Halle (Saale), Halle (Saale), Germany.
Med Klin (Munich). 2010 Nov;105(11):837-40. doi: 10.1007/s00063-010-1143-2. Epub 2010 Dec 7.
In patients with systemic sclerosis or mixed connective tissue disease (MCTD) acral ulcers are considered as frequent manifestations that may lead to amputation and loss of function, respectively, as a result of secondary Raynaud's phenomenon. Thus it is necessary to take advantage of all available medical and supportive measures. Adjuvant treatments such as hyperbaric oxygenation and regional sympathetic block represent interdisciplinary treatment options to improve oxygenation of critical ischemia and analgesia and should be subject of further investigation.
在系统性硬化症或混合性结缔组织病(MCTD)患者中,肢端溃疡被视为常见表现,分别可能由于继发性雷诺现象导致截肢和功能丧失。因此,有必要利用所有可用的医学和支持性措施。高压氧治疗和局部交感神经阻滞等辅助治疗是改善严重缺血性氧合和镇痛的跨学科治疗选择,应进一步研究。