Vossel S, Kukolja J, Fink G R
Institut für Neurowissenschaften und Medizin (INM-3)-Kognitive Neurologie, Forschungszentrum Jülich, Leo-Brandt-Strasse 5, Jülich.
Fortschr Neurol Psychiatr. 2010 Dec;78(12):733-45. doi: 10.1055/s-0029-1245862. Epub 2010 Dec 6.
Neglect is characterised by a clinically relevant impairment of spatial perception and awareness observed after focal brain damage. The neglect-specific deficit in responding to contralesional stimuli in various sensory modalities is most commonly explained by impairments of spatial attention, spatial working memory, impaired spatial reference frames and lateralised movement initiation. Many neglect interventions have been developed in the last decades to alleviate symptoms of neglect in stroke patients. However, hardly any of these methods has been proven to significantly ameliorate the patient's deficits in everyday activities. Thus, the identification of predictors for recovery of function and of the success of rehabilitative measures provides a major challenge for future research on neglect.
忽视症的特征是局灶性脑损伤后出现的具有临床相关性的空间感知和意识障碍。各种感觉模态中对患侧刺激反应的忽视特异性缺陷，最常见的解释是空间注意力、空间工作记忆、空间参照系受损以及单侧运动启动障碍。在过去几十年中，已经开发了许多忽视症干预措施来减轻中风患者的忽视症状。然而，这些方法几乎没有被证明能显著改善患者在日常活动中的缺陷。因此，确定功能恢复和康复措施成功的预测因素，对未来忽视症的研究提出了重大挑战。
