Schiff G D
General Medicine Clinic Section, Cook County Hospital, Chicago, IL 60612.
QRB Qual Rev Bull. 1990 Apr;16(4):149-55. doi: 10.1016/s0097-5990(16)30357-8.
The Joint Commission on Accreditation of Healthcare Organizations and the Food and Drug Administration (FDA) have encouraged hospitals to develop mechanisms to improve reporting of adverse drug reactions (ADRs). Cook County Hospital, in Chicago, introduced a check box on a computerized discharge summary form on which the physician codes for ADRs occurring during admission. Review of the data base for a two-year period disclosed 162 well-documented ADRs, many times greater than those generated in FDA reports. The patterns of ADRs found, actions taken in response, and strengths and limitations of this system for ADR screening are reviewed. This semispontaneous screening and reporting method is found to be a valuable tool for a local hospital's ADR program, with great potential for involving physicians and providing local feedback on ADR rates.
医疗保健组织认证联合委员会和食品药品监督管理局（FDA）鼓励医院建立机制，以改进药品不良反应（ADR）的报告。芝加哥的库克县医院在计算机化出院小结表格上设置了一个复选框，医生可在上面对住院期间发生的药品不良反应进行编码。对两年期间的数据库进行审查后发现了162例记录完备的药品不良反应，比FDA报告中的数量多出许多倍。本文回顾了所发现的药品不良反应模式、针对这些反应采取的措施以及该药品不良反应筛查系统的优点和局限性。这种半自发的筛查和报告方法被认为是当地医院药品不良反应项目的一项宝贵工具，在吸引医生参与以及提供有关药品不良反应发生率的本地反馈方面具有巨大潜力。
