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南卡罗来纳州流动农场工人子女的免疫接种延迟情况。

The delayed immunization of children of migrant farm workers in South Carolina.

作者信息

Lee C V, McDermott S W, Elliott C

机构信息

Department of Family and Preventive Medicine, University of South Carolina School of Medicine, Columbia 29208.

出版信息

Public Health Rep. 1990 May-Jun;105(3):317-20.

PMID:2113693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1579997/
Abstract

A study was conducted to evaluate the immunization status of migrant farm worker children in South Carolina. Results of this study indicate that the children receive their immunizations at times which are significantly later than the recommended schedule. The first, second, third, and fourth oral poliomyelitis vaccine (OPV) doses are being given approximately 10, 15, 23, and 32 months late, respectively. Diphtheria, pertussis, tetanus vaccine (DPT) is likewise late with the first, second, third, and fourth doses occurring 9, 14, 20, and 26 months late. The fifth booster dose in both series was timed properly. The mumps, measles, rubella vaccine (MMR) is approximately 28 months late, on average. An evaluation of antibody status of 41 migrant farm worker children (5-10 years old) revealed that, even with aberrant patterns of administration, all children had adequate antibody titers. These data indicate that, although adequate levels of protection are reached with the pattern of immunization that migrant farm worker children have, there are large groups of children that are unprotected early in life when they are most susceptible to these diseases.

摘要

一项研究旨在评估南卡罗来纳州流动农场工人子女的免疫接种状况。该研究结果表明,这些儿童接种疫苗的时间明显晚于推荐时间表。口服脊髓灰质炎疫苗(OPV)的第一、二、三、四剂接种时间分别晚约10、15、23和32个月。白喉、百日咳、破伤风疫苗(DPT)同样延迟,第一、二、三、四剂接种时间分别晚9、14、20和26个月。两个系列中的第五剂加强针接种时间合适。腮腺炎、麻疹、风疹疫苗(MMR)平均延迟约28个月。对41名流动农场工人子女(5至10岁)的抗体状况评估显示,即使接种模式异常,所有儿童的抗体滴度都足够。这些数据表明,尽管流动农场工人子女的免疫接种模式能达到足够的保护水平,但仍有大量儿童在生命早期最易感染这些疾病时未得到保护。

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本文引用的文献

1
Immunization and health care patterns of Louisiana two year-olds.路易斯安那州两岁儿童的免疫接种和医疗保健模式。
J La State Med Soc. 1985 Nov;137(11):48-50, 55-6.
2
Health problems of migrant children.流动儿童的健康问题。
J Sch Health. 1985 Dec;55(10):411-2. doi: 10.1111/j.1746-1561.1985.tb01166.x.
3
Measles outbreak in a fully immunized secondary-school population.在一所全员接种疫苗的中学人群中爆发麻疹。
N Engl J Med. 1987 Mar 26;316(13):771-4. doi: 10.1056/NEJM198703263161303.
4
DTP immunization status and tetanus antitoxin titers of Mexican American children ages six months through eleven years.6个月至11岁墨西哥裔美国儿童的白喉、破伤风、百日咳疫苗免疫状况及破伤风抗毒素滴度
Am J Public Health. 1988 Nov;78(11):1446-50. doi: 10.2105/ajph.78.11.1446.
5
Persistence of maternal antibody in infants beyond 12 months: mechanism of measles vaccine failure.12个月以上婴儿中母源抗体的持续存在:麻疹疫苗接种失败的机制
J Pediatr. 1977 Nov;91(5):715-8. doi: 10.1016/s0022-3476(77)81021-4.
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Measles immunization. Successes and failures.麻疹免疫。成功与失败。
JAMA. 1977 Jan 24;237(4):347-51.
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Further attenuated live measles vaccines: the need for revised recommendations.进一步减毒的麻疹活疫苗:修订建议的必要性。
J Pediatr. 1977 Nov;91(5):766-7. doi: 10.1016/s0022-3476(77)81036-6.
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Risk factors associated with failure to receive vaccinations.与未接种疫苗相关的风险因素。
Pediatrics. 1979 Sep;64(3):304-9.
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Epidemic measles in a highly vaccinated population.
N Engl J Med. 1977 Mar 17;296(11):585-9. doi: 10.1056/NEJM197703172961102.