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[利用自体荧光光谱法对气管和/或支气管恶性肿瘤治疗效果进行联合内镜监测]

[Combined endoscopic monitoring of treatment effectiveness in tracheal and/or bronchial malignancies using autofluorescence spectroscopy].

作者信息

Arsen'ev A I, Barchuk A A, Levchenko E V, Barchuk A S, Kulakova Iu A, Nefedov A O, Zhelbunova E A, Shcherbakov A M, Kanaev S V

出版信息

Vopr Onkol. 2010;56(5):548-51.

PMID:21137233
Abstract

The paper presents our experience with application of a diagnostic procedure which enhanced information potential of endoscopy. Its efficiency increased due to use of an algorithm which included several stages carried out during an endoscopic procedure: routine bronchoscopy, spectroscopy in light (400-700 nm), autofluorescence spectroscopy including nearest infrared spectrum (720-800 nm). During treatment, the latter registered the dynamics of glow intensity ratios in the red (600-680 nm) and green (500-550 nm) spectra. The efficacy of our method was determinated by the precise delineation of the involvement area and its changes in the course of treatment which matched final analysis data.

摘要

本文介绍了我们应用一种诊断程序的经验,该程序增强了内窥镜检查的信息潜力。由于使用了一种算法,其效率得到了提高,该算法包括在内窥镜检查过程中进行的几个阶段:常规支气管镜检查、光(400-700纳米)光谱学、包括近红外光谱(720-800纳米)的自体荧光光谱学。在治疗过程中,后者记录了红色(600-680纳米)和绿色(500-550纳米)光谱中发光强度比的动态变化。我们方法的有效性通过精确描绘受累区域及其在治疗过程中的变化来确定,这些变化与最终分析数据相符。

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