Chougnet Antoinette, Liu Kegang, Woggon Wolf D
Department of Chemistry, University of Basel, St. Johanns-Ring 19, CH-4056 Basel.
Chimia (Aarau). 2010;64(5):303-8. doi: 10.2533/chimia.2010.303.
We report here on our efforts to develop new strategies for the synthesis of alpha-tocopherol, the biologically most significant member of the vitamin E family. This review comprises five new methods to generate the chiral chromane of alpha-tocopherol with overall up to 29% yield from commercially available material and up to 94% de.
我们在此报告我们为开发合成α-生育酚（维生素E家族中生物学意义最为重要的成员）的新策略所做的努力。本综述包含五种生成α-生育酚手性色满的新方法，从市售原料出发，总收率高达29%，对映体过量率高达94%。
