Bogucki A
Department of Neurology, Medical Academy, Lòdz, Poland.
Cephalalgia. 1990 Apr;10(2):71-5. doi: 10.1046/j.1468-2982.1990.1002071.x.
Attacks of cluster headache provoked by the administration of nitroglycerin (1 mg sublingually) or histamine (0.01 mg/kg subcutaneously) were studied. The constant latency time in individual patients during nitroglycerin and histamine provocation suggested that the same mechanism is involved in both methods of headache induction. Repeated nitroglycerin provocation revealed its tendency to lengthen duration of the refractory period at the end of the bout, when the attacks were less frequent. The "cross studies" on spontaneous and nitroglycerin provoked attacks indicated that the underlying mechanism of both is at least partially the same.
研究了舌下含服硝酸甘油（1毫克）或皮下注射组胺（0.01毫克/千克）诱发的丛集性头痛发作。硝酸甘油和组胺激发试验中个体患者的潜伏期恒定，提示两种诱发头痛的方法涉及相同机制。反复进行硝酸甘油激发试验显示，在发作频率较低的发作末期，其有延长不应期持续时间的趋势。对自发性发作和硝酸甘油诱发发作的“交叉研究”表明，两者的潜在机制至少部分相同。
