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电子尼古丁传送系统:是否需要监管?

Electronic nicotine delivery systems: is there a need for regulation?

机构信息

Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, USA.

出版信息

Tob Control. 2011 Jan;20(1):47-52. doi: 10.1136/tc.2010.037259. Epub 2010 Dec 7.

DOI:10.1136/tc.2010.037259
PMID:21139013
Abstract

PURPOSE

Electronic nicotine delivery systems (ENDS) purport to deliver nicotine to the lungs of smokers. Five brands of ENDS were evaluated for design features, accuracy and clarity of labelling and quality of instruction manuals and associated print material supplied with products or on manufacturers' websites.

METHODS

ENDS were purchased from online vendors and analysed for various parameters.

RESULTS

While the basic design of ENDS was similar across brands, specific design features varied significantly. Fluid contained in cartridge reservoirs readily leaked out of most brands, and it was difficult to assemble or disassemble ENDS without touching nicotine-containing fluid. Two brands had designs that helped lessen this problem. Labelling of cartridges was very poor; labelling of some cartridge wrappers was better than labelling of cartridges. In general, packs of replacement cartridges were better labelled than the wrappers or cartridges, but most packs lacked cartridge content and warning information, and sometimes packs had confusing information. Used cartridges contained fluid, and disposal of nicotine-containing cartridges was not adequately addressed on websites or in manuals. Orders were sometimes filled incorrectly, and safety features did not always function properly. Print and internet material often contained information or made claims for which there is currently no scientific support.

CONCLUSIONS

Design flaws, lack of adequate labelling and concerns about quality control and health issues indicate that regulators should consider removing ENDS from the market until their safety can be adequately evaluated.

摘要

目的

电子尼古丁传送系统(ENDS)据称可将尼古丁传送到吸烟者的肺部。本文评估了 5 种品牌的 ENDS 的设计特点、标签的准确性和清晰度,以及产品随附的或制造商网站上提供的使用手册和相关印刷材料的质量。

方法

从在线供应商处购买 ENDS,并对其进行各种参数分析。

结果

尽管不同品牌的 ENDS 的基本设计相似,但具体设计特点差异很大。储液器中的液体很容易从大多数品牌中泄漏出来,而且如果不接触含有尼古丁的液体,就很难组装或拆卸 ENDS。有两个品牌的设计有助于减少这个问题。墨盒的标签很差;一些墨盒包装的标签比墨盒的标签好。总的来说,更换墨盒的包装比包装或墨盒的标签好,但大多数包装缺乏墨盒内容和警告信息,有时包装上的信息令人困惑。用过的墨盒中含有液体,而且网站或手册上没有充分说明如何处理含有尼古丁的墨盒。订单有时填写不正确,安全功能也不一定正常工作。印刷和互联网材料经常包含目前没有科学依据支持的信息或声明。

结论

设计缺陷、标签不充分以及对质量控制和健康问题的关注表明,监管机构应考虑将 ENDS 从市场上撤下,直到能够充分评估其安全性。

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