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以产生癌胚抗原的直肠癌形式出现的多发性骨髓瘤。

Multiple myeloma presenting as CEA-producing rectal cancer.

作者信息

Talamo Giampaolo, Barochia Amitkumar, Zangari Maurizio, Loughran Thomas P

机构信息

Penn State Hershey Cancer Institute, Hershey, PA, USA.

出版信息

Rare Tumors. 2010 Mar 31;2(1):e4. doi: 10.4081/rt.2010.e4.

DOI:10.4081/rt.2010.e4
PMID:21139949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2994484/
Abstract

We report the case of a 57-year-old patient with multiple myeloma, characterized by extramedullary involvement of the rectum at presentation. Malignant plasma cells were found to produce carcinoembryonic antigen (CEA), a tumor antigen more commonly associated with rectal adenocarcinomas.

摘要

我们报告了一例57岁的多发性骨髓瘤患者，其特征为就诊时直肠出现髓外浸润。发现恶性浆细胞产生癌胚抗原（CEA），这是一种更常见于直肠腺癌的肿瘤抗原。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/cb23eb912789/rt-2010-1-e4-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/a6de1f25963d/rt-2010-1-e4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/9673321e5f94/rt-2010-1-e4-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/cb23eb912789/rt-2010-1-e4-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/a6de1f25963d/rt-2010-1-e4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/9673321e5f94/rt-2010-1-e4-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3767/2994484/cb23eb912789/rt-2010-1-e4-g003.jpg

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本文引用的文献

1
Association of multiple myeloma and inflammatory bowel diseases.多发性骨髓瘤与炎症性肠病的关联。
Dig Dis Sci. 2008 Mar;53(3):863-4. doi: 10.1007/s10620-007-9932-z. Epub 2007 Aug 24.
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Review article: multiple myeloma and inflammatory bowel disease.
Dig Dis Sci. 2007 Sep;52(9):2022-8. doi: 10.1007/s10620-006-9165-6. Epub 2007 Apr 10.
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Carcinoembryonic antigen-producing multiple myeloma detected by a transcription-reverse transcription concerted reaction system.
Int J Hematol. 2007 Feb;85(2):128-31. doi: 10.1532/IJH97.06169.
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Clinical and biological features of multiple myeloma involving the gastrointestinal system.累及胃肠道系统的多发性骨髓瘤的临床和生物学特征
Haematologica. 2006 Jul;91(7):964-7.
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Features of extramedullary and extraosseous multiple myeloma: a report of 19 patients from a single center.髓外和骨外多发性骨髓瘤的特征：来自单一中心的19例患者报告
Eur J Haematol. 2004 Dec;73(6):402-6. doi: 10.1111/j.1600-0609.2004.00331.x.
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Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group.单克隆丙种球蛋白病、多发性骨髓瘤及相关疾病的分类标准：国际骨髓瘤工作组报告
Br J Haematol. 2003 Jun;121(5):749-57.
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Extramedullary plasmacytoma: clinical and histopathologic study.髓外浆细胞瘤：临床与组织病理学研究
Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):692-701. doi: 10.1016/s0360-3016(02)02780-3.
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Expression of CD66a in multiple myeloma.CD66a在多发性骨髓瘤中的表达。
J Clin Lab Anal. 2002;16(2):79-85. doi: 10.1002/jcla.10020.
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Carcinoembryonic antigen: cell adhesion molecule and useful diagnostic marker.癌胚抗原：细胞粘附分子及有用的诊断标志物。
Br J Biomed Sci. 1999;56(3):209-14.
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Carcinoembryonic antigen in staging and follow-up of patients with solid tumors.
Tumour Biol. 1995;16(1):32-41. doi: 10.1159/000217926.