Yadav Siddhartha, Kumar Ramesh, Jaiyesimi Ishmael A, Chisti Mohammad Muhsin
Department of Internal Medicine, William Beaumont Hospital, Royal Oak, Michigan, USA.
BMJ Case Rep. 2013 Oct 29;2013:bcr2013200607. doi: 10.1136/bcr-2013-200607.
A man in his early 40s with a history of ulcerative colitis, treated with infliximab, was diagnosed with plasmablastic multiple myeloma. He was treated with chemotherapy and stem cell transplant but developed recurrence and ultimately died from metastatic disease. Could inflammatory bowel disease or infliximab therapy have any role in development of myeloma in this young patient? The role of inflammatory bowel disease and infliximab therapy in the development of multiple myeloma is controversial but interesting and worth considering.
一名40岁出头、有溃疡性结肠炎病史且接受英夫利昔单抗治疗的男性被诊断为浆母细胞性多发性骨髓瘤。他接受了化疗和干细胞移植，但疾病复发，最终死于转移性疾病。炎症性肠病或英夫利昔单抗治疗在这位年轻患者的骨髓瘤发生过程中会起作用吗？炎症性肠病和英夫利昔单抗治疗在多发性骨髓瘤发生中的作用存在争议，但很有趣且值得探讨。
