Elnemr Ayman, Yonemura Yutaka, Shinbo Masaya, Nishino Eisei
NPO Organization to Support Peritoneal Surface Malignancy Treatment, Japan;
Rare Tumors. 2010 Mar 31;2(1):e6. doi: 10.4081/rt.2010.e6.
Mullerian tumors are extremely rare malignancies in the retroperitoneum. We report a case of a 46-year old woman who presented with an eight year history of lower abdominal mass. Ultrasonography (US) and computed tomography (CT) demonstrated a 15×10 cm cystic mass in the left lower retroperitoneum. As serial percutaneous needle aspiration cytology was negative for malignancy, she was observed for seven years. Eleven months ago, the mass was excised. The histopathology was reported as mucinous adenocarcinoma of the retroperitoneum. Six cycles of intraperitoneal (IP) chemotherapy was administered during the last six months after diagnosis of recurrence by aspiration cytology and high serum tumor markers (CEA, CA19-9). A few days ago, positron emission tomographic (PET) scanning showed evidence of local recurrence and single vertebral metastasis, so she was admitted again for systemic chemotherapy. Meticulous revision of additional sections of the tumor revealed papillary, serous, mucinous, and endometrioid subtypes of the mullerian adenocarcinoma. To our knowledge, there has been no similar case described in the literature.
苗勒管肿瘤是腹膜后极为罕见的恶性肿瘤。我们报告一例46岁女性，有8年下腹部肿块病史。超声（US）和计算机断层扫描（CT）显示左下腹腹膜后有一个15×10 cm的囊性肿块。由于连续经皮针吸细胞学检查未发现恶性肿瘤，对她进行了7年的观察。11个月前，切除了肿块。组织病理学报告为腹膜后黏液腺癌。在通过针吸细胞学检查和高血清肿瘤标志物（癌胚抗原、糖类抗原19-9）诊断复发后的最后6个月内，进行了6个周期的腹腔内（IP）化疗。几天前，正电子发射断层扫描（PET）显示有局部复发和单个椎体转移的迹象，因此她再次入院接受全身化疗。对肿瘤其他切片的仔细检查发现了苗勒管腺癌的乳头状、浆液性、黏液性和子宫内膜样亚型。据我们所知，文献中尚未描述过类似病例。
