Masoodi Ibrahim, Farooq Omar, Ahmad Iqbal, Bhat Mohammad Yaseen, Ahmad Nazir, Wani Hamid-ullah, Dar Javeed Ahmad
Division of Gastroenterology, King Fahad Medical City, Riyadh, Saudi Arabia.
Ger Med Sci. 2010 Nov 18;8:Doc32. doi: 10.3205/000121.
Acute disseminated encephalomyelitis (ADEM) also known as post infectious encephalomyelitis is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurological symptoms and disability. It may follow vaccination in children or infection. Viral infection like measles, rubella, influenza, Epstein bar, HIV, herpes, cytomegalusvirus (CMV) and West Nile virus have been implicated in the causation. Among bacteria, group A hemolytic streptococcus, mycoplasma pneumonia, Chlamydia, Rickettesia and leptospira have been shown to cause ADEM. There are few reports of ADEM due to tuberculosis (TB). We describe acute disseminated encephalomyelitis due to tuberculosis in a 35 year old female who initially started with neuropsychiatric manifestations and later developed florid neurological deficit and classical magnetic resonance imaging (MRI) lesions suggestive of the disease. The patient recovered completely after antitubercular therapy and is following our clinic for the last 12 months now.
急性播散性脑脊髓炎（ADEM），也称为感染后脑脊髓炎，是一种中枢神经系统（CNS）脱髓鞘疾病，通常表现为单相性疾病，伴有多灶性神经症状和功能障碍。它可能发生在儿童接种疫苗后或感染后。病毒感染如麻疹、风疹、流感、EB病毒、艾滋病毒、疱疹、巨细胞病毒（CMV）和西尼罗河病毒与病因有关。在细菌中，A组溶血性链球菌、肺炎支原体、衣原体、立克次体和钩端螺旋体已被证明可引起ADEM。因结核病（TB）导致ADEM的报道很少。我们描述了一名35岁女性因结核病引起的急性播散性脑脊髓炎，该患者最初出现神经精神症状，后来出现明显的神经功能缺损和典型的磁共振成像（MRI）病变，提示患有该病。患者在抗结核治疗后完全康复，目前在我们诊所随访了12个月。
