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美国的获得性免疫缺陷综合征与肺外结核病

Acquired immunodeficiency syndrome and extrapulmonary tuberculosis in the United States.

作者信息

Braun M M, Byers R H, Heyward W L, Ciesielski C A, Bloch A B, Berkelman R L, Snider D E

机构信息

Division of HIV/AIDS, Centers for Disease Control, Atlanta, GA 30333.

出版信息

Arch Intern Med. 1990 Sep;150(9):1913-6.

PMID:2393321
Abstract

Of 48,712 acquired immunodeficiency syndrome (AIDS) cases reported to the Centers for Disease Control from October 1987 through March 1989, 1239 (2.5%) were diagnosed with extrapulmonary tuberculosis. Extrapulmonary tuberculosis was diagnosed in 1013 (2.3%) of the US-born persons with AIDS, compared with 26 (8%) of the Mexican-born, 82 (13%) of the Haitian-born, and 4 (1%) of the Cuban-born. Patients with AIDS with and without extrapulmonary tuberculosis were similar in age, except that extrapulmonary tuberculosis was relatively rare in patients with AIDS under the age 10. Compared with white homosexual/bisexual men, black race (odds ratio, 2.7), intravenous drug use (odds ratio, 2.0), heterosexual AIDS transmission category (odds ratio, 1.9), and Hispanic ethnicity (odds ratio, 1.6) were independently associated with extrapulmonary tuberculosis. In 1988, extrapulmonary tuberculosis in persons known to be human immunodeficiency virus seropositive represented 21% of national extrapulmonary tuberculosis morbidity.

摘要

在1987年10月至1989年3月期间向疾病控制中心报告的48712例获得性免疫缺陷综合征(艾滋病)病例中,有1239例(2.5%)被诊断为肺外结核。在美国出生的艾滋病患者中,1013例(2.3%)被诊断为肺外结核,相比之下,在墨西哥出生的患者中有26例(8%),在海地出生的患者中有82例(13%),在古巴出生的患者中有4例(1%)。患有和未患有肺外结核的艾滋病患者在年龄上相似,只是在10岁以下的艾滋病患者中肺外结核相对少见。与白人同性恋/双性恋男性相比,黑人种族(比值比为2.7)、静脉吸毒(比值比为2.0)、异性传播艾滋病类别(比值比为1.9)和西班牙裔(比值比为1.6)与肺外结核独立相关。1988年,已知人类免疫缺陷病毒血清呈阳性者中的肺外结核占全国肺外结核发病率的21%。

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