Josko Deborah
Department of Clinical Laboratory Sciences, Medical Laboratory Science Program, University of Medicine and Dentistry of New Jersey, 1776 Raritan Road, Scotch Plains, NJ 07076, USA.
Clin Lab Sci. 2010 Fall;23(4):237-41.
Identifying organisms in a timely manner has always been one of the greatest challenges for clinical microbiologists. Healthcare providers want rapid results in order to prescribe the appropriate antimicrobial therapy and improve patient care. Some of the more virulent pathogens such as MRSA, VRE, and MTB must be identified as quickly and accurately as possible in order to prevent the spread of the disease to other patients and employees. The need for rapid, molecular methodologies in the clinical bacteriology laboratory was essential to improve patient outcomes. Organisms that use to take days or weeks to identify are now detected in hours or within the same day. The advent of molecular assays has enabled clinical laboratory scientists to report out accurate, sensitive and timely results confirming the critical role they play on the healthcare team.
及时鉴定病原体一直是临床微生物学家面临的最大挑战之一。医疗服务提供者希望获得快速结果，以便开出适当的抗菌治疗方案并改善患者护理。一些毒性更强的病原体，如耐甲氧西林金黄色葡萄球菌（MRSA）、耐万古霉素肠球菌（VRE）和结核分枝杆菌（MTB），必须尽快准确鉴定，以防止疾病传播给其他患者和员工。临床细菌学实验室对快速分子方法的需求对于改善患者预后至关重要。过去需要数天或数周才能鉴定的病原体现在数小时内或同一天就能检测出来。分子检测方法的出现使临床实验室科学家能够报告准确、灵敏且及时的结果，证实了他们在医疗团队中所发挥的关键作用。
