Silverberg Nanette B
Pediatric and Adolescent Dermatology, St. Luke's-Roosevelt Hospital Center, 1090 Amsterdam Ave, Ste 11D, New York, NY 10025, USA.
Cutis. 2010 Oct;86(4):172-6.
Pediatric psoriasis is an autoimmune diathesis with a complex immunologic basis. It is associated with extensive psychological morbidity and should be treated rapidly and effectively to limit psychologic effects on children. The most common trigger in childhood is upper respiratory tract infection. Once disease has occurred, treatment is based on severity and presence of joint involvement. Topical therapies include corticosteroids and calcipotriene. UV light, systemic retinoids, and cyclosporine remit cutaneous psoriatic lesions. Methotrexate sodium and etanercept benefit both skin and joint manifestations of psoriasis. Concern for psychological symptoms and psychological growth is needed in treating pediatric patients with psoriasis vulgaris.
儿童银屑病是一种具有复杂免疫基础的自身免疫素质。它与广泛的心理疾病相关,应迅速有效地治疗以限制对儿童的心理影响。儿童最常见的诱发因素是上呼吸道感染。一旦发病,治疗基于病情严重程度和关节受累情况。局部治疗包括使用皮质类固醇和卡泊三醇。紫外线光、全身性维甲酸和环孢素可缓解皮肤银屑病皮损。甲氨蝶呤钠和依那西普对银屑病的皮肤和关节表现均有益处。在治疗寻常型儿童银屑病患者时,需要关注其心理症状和心理成长。