Lyko Christina, Bart Pierre-Alexandre, Pruvot Etienne, Prior John, Waeber Gérard
Service de médecine interne, CHUV, Lausanne.
Rev Med Suisse. 2010 Nov 3;6(269):2056-60.
Sarcoidosis is a multi-systemic inflammatory disease of unknown etiology, histologically characterized by the presence of non caseating granulomas. The diagnostic suspicion relies on clinical, epidemiological, biological and radiological elements. It is confirmed by an evocative histology and by the exclusion of other granulomatous pathologies. The aim of this article is to expose some clinical manifestations of extrapulmonary sarcoidosis particularly the cardiac and abdominal involvements. A register was made on cases of sarcoidosis diagnosed in CHUV from 2000 to 2009. It demonstrates the rarity of the disease in the region of Lausanne and confirms the existence of purely extra-thoracic affections.
结节病是一种病因不明的多系统炎症性疾病,组织学特征为非干酪样肉芽肿的存在。诊断怀疑依赖于临床、流行病学、生物学和放射学因素。通过具有提示性的组织学检查并排除其他肉芽肿性病变来确诊。本文的目的是阐述肺外结节病的一些临床表现,特别是心脏和腹部受累情况。对2000年至2009年在洛桑大学中心医院(CHUV)诊断的结节病病例进行了登记。该登记显示了洛桑地区该病的罕见性,并证实了纯胸外受累情况的存在。