Department of Advanced Therapy for Spine and Spinal Cord Disorders.
J Neurosurg Spine. 2011 Jan;14(1):51-8. doi: 10.3171/2010.9.SPINE09933. Epub 2010 Dec 10.
to reduce intraoperative damage to the posterior supporting structures of the lumbar spine during decompressive surgery for lumbar canal stenosis (LCS), lumbar spinous process-splitting laminectomy (LSPSL or split laminectomy) was developed. This prospective, randomized, controlled study was conducted to clarify whether the split laminectomy decreases acute postoperative wound pain compared with conventional laminectomy.
forty-one patients with LCS were enrolled in this study. The patients were randomly assigned to either the LSPSL group (22 patients) or the conventional laminectomy group (19 patients). Questionnaires regarding wound pain (intensity, depth, and duration) and activities of daily living (ADL) were administered at postoperative days (PODs) 3 and 7. Additionally, the authors evaluated the pre- and postoperative serum levels of C-reactive protein and creatine phosphokinase, the amount of pain analgesics used during a 3-day postoperative period, and the muscle atrophy rate measured on 1-month postsurgical MR images.
data obtained in patients in the LSPSL group and in 16 patients in the conventional laminectomy group were analyzed. The mean visual analog scale for wound pain on POD 7 was significantly lower in the LSPSL group (16 ± 17 mm vs 34 ± 31 mm, respectively; p = 0.04). The mean depth-of-pain scores on POD 7 were significantly lower in the LSPSL group than in the conventional group (0.9 ± 0.6 vs 1.7 ± 0.8, respectively; p = 0.013). On POD 3, the mean serum creatine phosphokinase level was significantly lower in the LSPSL group (126 ± 93 U/L) than in the other group (207 ± 150 U/L) (p = 0.02); on POD 7, the mean serum C-reactive protein level was significantly lower in the LSPSL group (1.1 ± 0.6 mg/dl) than in the conventional laminectomy group (1.9 ± 1.5 mg/dl) (p = 0.04). The number of pain analgesics taken during the 3-day postoperative period was lower in the LSPSL group than in the conventional laminectomy group (1.7 ± 1.3 tablets vs 2.3 ± 2.4 tablets, respectively; p = 0.22). The mean muscle atrophy rate was also significantly lower in the LSPSL group (24% ± 15% vs 43% ± 22%; p = 0.004).
lumbar spinous process-splitting laminectomy for the treatment of LCS reduced acute postoperative wound pain and prevented postoperative muscle atrophy compared with conventional laminectomy, possibly because of minimized damage to the paraspinal muscles.
在腰椎管狭窄症(LCS)减压手术中,为减少对腰椎后路支持结构的术中损伤,开发了腰椎棘突劈开椎板切除术(LSPSL 或劈开椎板切除术)。本前瞻性、随机、对照研究旨在阐明与传统椎板切除术相比,劈开椎板切除术是否能减轻急性术后伤口疼痛。
本研究纳入了 41 例 LCS 患者。将患者随机分配至 LSPSL 组(22 例)或传统椎板切除术组(19 例)。在术后第 3 天和第 7 天,使用问卷调查评估伤口疼痛(强度、深度和持续时间)和日常生活活动(ADL)。此外,作者评估了术前和术后第 3 天血清 C 反应蛋白和肌酸磷酸激酶水平、3 天术后期间使用的止痛剂数量以及术后 1 个月 MRI 上的肌肉萎缩率。
对 LSPSL 组和传统椎板切除术组的 22 例患者和 16 例患者的数据进行了分析。LSPSL 组术后第 7 天的平均伤口疼痛视觉模拟评分显著低于传统椎板切除术组(16 ± 17 mm 比 34 ± 31 mm;p = 0.04)。LSPSL 组术后第 7 天的平均疼痛深度评分显著低于传统组(0.9 ± 0.6 比 1.7 ± 0.8;p = 0.013)。术后第 3 天,LSPSL 组血清肌酸磷酸激酶水平显著低于另一组(126 ± 93 U/L)(207 ± 150 U/L)(p = 0.02);术后第 7 天,LSPSL 组血清 C 反应蛋白水平显著低于传统椎板切除术组(1.1 ± 0.6 mg/dl)(1.9 ± 1.5 mg/dl)(p = 0.04)。LSPSL 组术后 3 天内使用的止痛药数量也低于传统椎板切除术组(1.7 ± 1.3 片比 2.3 ± 2.4 片;p = 0.22)。LSPSL 组的平均肌肉萎缩率也显著较低(24% ± 15%比 43% ± 22%;p = 0.004)。
与传统椎板切除术相比,LSPSL 治疗 LCS 可减轻急性术后伤口疼痛并预防术后肌肉萎缩,这可能是由于对椎旁肌肉的损伤最小化所致。