Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany.
Med J Aust. 2010;193(11-12):730-4. doi: 10.5694/j.1326-5377.2010.tb04127.x.
To compare the efficacy of applying hot dry air versus dry air at room temperature to the throat of patients with a newly acquired common cold using a symptom severity score.
DESIGN, SETTING AND PARTICIPANTS: A randomised single-blind controlled trial with a treatment duration of 3 days and a follow-up period of 4 days was conducted at a sauna in Berlin, Germany. Between November 2007 and March 2008 and between September 2008 and April 2009, 157 patients with symptoms of the common cold were randomly assigned to an intervention group (n=80) and a control group (n=77).
Participants in the intervention group inhaled hot dry air within a hot sauna, dressed in a winter coat, whereas participants in the control group inhaled dry air at room temperature within a hot sauna, also dressed in a winter coat.
Area under the curve (AUC) summarising symptom severity over time (Days 2, 3, 5 and 7), symptom severity scores for individual days, intake of medication for the common cold and general ill feeling.
No significant difference between groups was observed for AUC representing symptom severity over time (intervention group mean, 31.2 [SEM, 1.8]; control group mean, 35.1 [SEM, 2.3]; group difference, -3.9 [95% CI, -9.7 to 1.9]; P=0.19). However, significant differences between groups were found for medication use on Day 1 (P=0.01), symptom severity score on Day 2 (P=0.04), and participants' ratings of the effectiveness of the therapy on Day 7 (P=0.03).
Inhaling hot air while in a sauna has no significant impact on overall symptom severity of the common cold.
ClinicalTrials.gov identifier NCT00552981.
通过症状严重程度评分，比较对新患普通感冒的患者喉咙应用热干空气与室温干燥空气的疗效。
设计、设置和参与者：在德国柏林的一家桑拿浴室进行了一项为期 3 天的治疗期和为期 4 天的随访期的随机单盲对照试验。2007 年 11 月至 2008 年 3 月和 2008 年 9 月至 2009 年 4 月期间，157 名患有普通感冒症状的患者被随机分配到干预组（n=80）和对照组（n=77）。
干预组患者在热桑拿室内吸入热干空气，并穿着冬季外套，而对照组患者在热桑拿室内吸入室温干燥空气，也穿着冬季外套。
总结随时间推移（第 2、3、5 和 7 天）症状严重程度的曲线下面积（AUC），个别天的症状严重程度评分，普通感冒药物的摄入和总体不适感觉。
两组间在代表随时间推移的症状严重程度的 AUC 方面无显著差异（干预组平均，31.2[SEM，1.8]；对照组平均，35.1[SEM，2.3]；组间差异，-3.9[95%CI，-9.7 至 1.9]；P=0.19）。然而，在第 1 天的药物使用（P=0.01）、第 2 天的症状严重程度评分（P=0.04）和第 7 天的治疗效果评估（P=0.03）方面，两组间存在显著差异。
在桑拿浴室中吸入热空气对普通感冒的整体症状严重程度没有显著影响。
ClinicalTrials.gov 标识符 NCT00552981。
