A prospective study of systolic ejection murmurs and left ventricular outflow tract in boxers.
作者信息
Höglund K, Häggström J, Bussadori C, Kvart C
机构信息
Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.
出版信息
J Small Anim Pract. 2011 Jan;52(1):11-7. doi: 10.1111/j.1748-5827.2010.01009.x. Epub 2010 Dec 9.
OBJECTIVES
To investigate the prevalence and progression of murmurs and the development of the left ventricular outflow tract (LVOT) and flow velocities in the great arteries in boxer puppies through adolescence until three years of age.
METHODS
Nineteen boxer puppies with or without a low-intensity murmur, but without evidence of congenital heart disease, were studied prospectively. Examinations were carried out at 7 weeks, 3, 4, 6, 9, 12 and 36 months of age by cardiac auscultation and Doppler echocardiography.
RESULTS
Presence and intensity of heart murmurs varied in the same dog and between dogs, but flow velocities did not change. Estimated effective orifice diameter (EOD) and indexed EOD was significantly narrower than measured subvalvular and valvular diameters.
CLINICAL SIGNIFICANCE
The variability in presence and intensity of low-intensity ejection murmurs is high during growth in boxers.
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